Advertisement

Primary liposarcoma of the mediastinum

  • Takenori Mase
  • Nobuhiko Kawawaki
  • Chihiro Narumiya
  • Takahiko Aoyama
  • Shinji Kato
  • Yoshihisa Nagata
Article

Abstract

Primary mediastinal liposarcomas are extremely rare malignancies that remain asymptomatic until large and, even then, initial symptoms, are nonspecific. We report a 48-year-old man followed up for asymptomatic multiple bullae who suffered progressive weight loss and dyspnea on exertion. Radiography and computed tomography of the chest showed a large mass with calcified nodules in the left pleural cavity and giant bullae in the right pleural cavity. Previous computed tomography of the chest showed a small tumor of mediastinal adipose tissue with calcified nodules. Tumor growth was calculated at about 500 times the tumor volume per 3.6 years. We completely resected the mediastinal tumor and conducted a bullectomy through a median sternotomy. The microscopic pathological diagnosis was well-differentiated/sclerosing liposarcoma. The man underwent no postoperative adjunctive irradiation and remains well 8 months after surgery.

Key words

primary mediastinal liposarcoma giant bullae CT-guided large-core needle biopsy tumor growth rate 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Carroll F, Kramer MD, Acinapura AJ, Tietjen PA, Wagner I, Oiseth S, et al. Pleural liposarcoma presenting with respiratory distress and suspected diaphragmatic hernia. Ann Thorac Surg 1992; 54: 1212–3.PubMedCrossRefGoogle Scholar
  2. 2.
    Jung JI, Kim H, Kang SW, Park SH. Radiological findings in myxoid liposarcoma of the anterior mediastinum Br J Radiol 1998; 71: 975–6PubMedGoogle Scholar
  3. 3.
    Wong WW, Pluth JR, Grado GL, Schild SE, Sanderson DR. Liposarcoma of the pleura. Mayo Clin Proc 1994; 69: 882–5.PubMedGoogle Scholar
  4. 4.
    Alvarez-Sala R, Casadevall J, Caballero P, Prados B, Ortega B. Long-term survival in a surgically treated nonencapsulated mediastinal primary liposarcoma: diagnostic utility of core-needle biopsy for mediastinal tumors. J Cardiovasc Surg 1995; 36: 199–200.Google Scholar
  5. 5.
    Chiyo M, Fujisawa T, Yasukawa T, Shiba M, Shibuya K, Sekine Y, et al. Successful resection of a primary liposarcoma in the anterior mediastinum in a child: report of a case. Surg Today 2001; 31: 230–2.PubMedCrossRefGoogle Scholar
  6. 6.
    Grewal RG, Prager K, Austin JH, Rotterdam H. Longterm survival in nonencapsulated primary liposarcoma of the mediastinum. Thorax 1993; 48: 1276–7.PubMedCrossRefGoogle Scholar
  7. 7.
    Okby NT, Travis WD. Liposarcoma of the pleural cavity: clinical and pathologic features of 4 cases with a review of the literature. Arch Pathol Lab Med 2000; 124: 699–703.PubMedGoogle Scholar
  8. 8.
    Iqbal M, Posen J, Bhuiya TA, Lackner RP, Steinberg HN, Rossoff LJ. Lymphocyte-rich pleural liposarcoma mimicking pericardial cyst. J Thorac Cardiovasc Surg 2000; 120: 610–2.PubMedCrossRefGoogle Scholar
  9. 9.
    Klimstra DS, Moran CA, Perino G, Koss MN, Rosai J. Liposarcoma of the anterior mediastinum and thymus. A clinicopathologic study of 28 cases. Am J Surg Pathol 1995; 19: 782–91.PubMedGoogle Scholar
  10. 10.
    Kiyama H, Tanabe S, Nagasawa S, Irie Y, Ohshima T, Yamada T. A case of primary anterior mediastinal liposarcoma with a heterotopic mass in the pericardium of the same histology (Eng abstr). J Jpn Assn Thorac Surg 1996; 44: 2191–5.Google Scholar

Copyright information

© The Japanese Society of Thoracic and Cardiovascular Surgery 2002

Authors and Affiliations

  • Takenori Mase
    • 1
  • Nobuhiko Kawawaki
    • 1
  • Chihiro Narumiya
    • 1
  • Takahiko Aoyama
    • 1
  • Shinji Kato
    • 1
  • Yoshihisa Nagata
    • 1
  1. 1.Department of Cardiovascular and Thoracic SurgeryAichi Medical University, School of MedicineAichiJapan

Personalised recommendations