Canadian Anaesthetists’ Society Journal

, Volume 20, Issue 1, pp 81–93 | Cite as

Blood serum fluoride levels with methoxyflurane anaesthesia

  • Allen B. Dobkin
  • Ashley A. Levy


Halothane Enflurane Methoxyflurane Fluothane Flurane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Pringle, H., Maunsell, R.C.B., &Pringle, S. Clinical effects of ether anaesthesia on renal activity. Brit. Med. J.2: 542 (1905).Google Scholar
  2. 2.
    Thompson, W.H. Preliminary note on renal activity during anaesthesia. Brit. Med. J.1: 649 (1905).Google Scholar
  3. 3.
    Smith, H.W., Rovenstine, al. The effect of spinal anesthesia on the circulation in normal unoperated man with reference to the anatomy of the arteriole and especially to those of the renal circulation. J. Clin. Invest.18: 319 (1939).PubMedCrossRefGoogle Scholar
  4. 4.
    Miles, B.E. &DeWardener, H.E. Renal vasoconstriction produced by ether and cyclopropane anaesthesia. J. Physiol118: 140 (1952).PubMedGoogle Scholar
  5. 5.
    Papper, S. &Papper, E.M. The effects of preanesthetic, anesthetic and postanesthetic drugs on renal function. Clin. Pharmacol. & Therap.5: 205 (1964).Google Scholar
  6. 6.
    Mueller, C.B. The mechanism of acute renal failure after injury and transfusion reaction and its prevention by solute diuresis. Surg. Clin. N.A.45: 499 (1965).Google Scholar
  7. 7.
    Schreiner, G.E. &Maher, J.F. Drugs and the kidney. Ann. N.Y. Acad. Sci.123: 326 (1965).PubMedGoogle Scholar
  8. 8.
    Artusio, J.F., VanPoznak, A., &Hunt, R.E.,et al. A clinical evaluation of methoxyflurane in man. Anesthesiology21: 512 (1960).PubMedGoogle Scholar
  9. 9.
    Paddock, R.B., Parker, J.W., &Guadagni, N.P. The effects of methoxyflurane on renal function. Anesthesiology25: 707 (1964).PubMedCrossRefGoogle Scholar
  10. 10.
    Crandell, W.B., Pappas, S.G., &MacDonald, A. Nephrotoxicity associated with methoxyflurane anesthesia. Anesthesiology27: 591 (1966).PubMedCrossRefGoogle Scholar
  11. 11.
    Dobkin, A.B. Methoxyflurane for major abdominal surgery. Abbott monograph No. 13, Jan. (1968).Google Scholar
  12. 12.
    Dobkin, A.B. & Byles, P.H. New Inhalation Anesthetics, chapter 12 in A Decade of Clinical Progress, ed. L.W. Fabian. Clinical Anesthesia3: 295 (1969).Google Scholar
  13. 13.
    Crandell, W.B. &MacDonald, A. Nephropathy associated with methoxyflurane anesthesia: a follow-up report. J.A.M.A.205: 798 (1968).PubMedCrossRefGoogle Scholar
  14. 14.
    Kuzucu, E.Y. Methoxyflurane, tetracycline and renal failure. J.A.M.A.211: 1162 (1970).PubMedCrossRefGoogle Scholar
  15. 15.
    Albers, D.D., Leverett, C.L. &Sandin, J.H. Renal failure following prostatovesiculectomy related to methoxyflurane and tetracycline — complicated by Candida infection. J. Urol.106: 348 (1971).PubMedGoogle Scholar
  16. 16.
    Lapointe, A. &Bele-Binda, N. Nephrotoxicity associated with methoxyflurane. Canad. Anaesth. Soc. J.17: 145 (1970).PubMedCrossRefGoogle Scholar
  17. 17.
    Committee on Anesthesia — National Academy of Sciences — National Research Council: Statement regarding the role of methoxyflurane in the production of renal dysfunction. Anesthesiology34: 505 (1971).CrossRefGoogle Scholar
  18. 18.
    Jones, N.O. Methoxyflurane nephrotoxicity — a review and a case report. Canad. Anaesth. Soc. J.19: 152 (1972).PubMedCrossRefGoogle Scholar
  19. 19.
    Van Dyke, R.A. &Chenoweth, M.B. Metabolism of volatile anesthetics. Anesthesiology26: 348 (1965).Google Scholar
  20. 20.
    Taves, D.R., Fry, B.W., Freeman, R.B., &Gillies, A.J. Toxicity following methoxyflurane anesthesia. II. Fluoride concentrations in nephrotoxicity. J.A.M.A.214: 91 (1970).PubMedCrossRefGoogle Scholar
  21. 21.
    Mazze, R.I., Trudell, J.R., &Cousins, M.J. Methoxyflurane metabolism and renal dysfunction: clinical correlation in man. Anesthesiology35: 247 (1971).PubMedCrossRefGoogle Scholar
  22. 22.
    Editorial: Fluorides and human health. Lancetii: 351 (1970).Google Scholar
  23. 23.
    Taves, D.R. New approach to the treatment of bone disease with fluoride. Fed. Proc.29: 1185 (1970).PubMedGoogle Scholar
  24. 24.
    Black, M.M., Kleiner, I.S., &Bolker, H. Toxicity of sodium fluoride in man. N.Y. State J. Med.49: 1187 (1949).PubMedGoogle Scholar
  25. 25.
    Goldemberg, L. Tratamiento de la enfermedad de Basedow ’y del hipertiroidismo por fluor. Rev. Soc. Med. Int. Soc. Tisiolog.6: 217 (1931).Google Scholar
  26. 26.
    Cousins, M.J., Nishimura, T.G., &Mazze, R.I. Renal effects of low-dose methoxyflurane with cardiopulmonary bypass. Anesthesiology36: 278 (1972).CrossRefGoogle Scholar
  27. 27.
    Fry, B.W. &Taves, D.R. Serum fluoride analysis with the fluoride electrode. J. Lab. & Clin. Med.75: 1020 (1970).Google Scholar
  28. 28.
    Dobkin, A.B., Byles, P.H., &Arandia, H.Y.,et al. Comparative metabolic responses to halogenated anaesthetics. Acta Anesth. Scandinav.16: 69 (1972).CrossRefGoogle Scholar
  29. 29.
    Van Dyke, R.A. Personal communication (1972).Google Scholar
  30. 30.
    Dobkin, A.B. &Fedoruk, S. Comparison of the cardiovascular, respiratory and metabolic effects of methoxyflurane and halothane in dogs. Anesthesiology22: 355 (1961).PubMedGoogle Scholar
  31. 31.
    Dobkin, A.B. & Byles, P.H. Comparison of anaesthesia with Innovar, halothane and methoxyflurane-nitrous oxide. Acta Anaesth. Scandinav.10: Suppl. 18 (1966).Google Scholar
  32. 32.
    Dobkin, A.B., Byles, P.H., &Neville, J.F., Jr. Neuroendocrine and metabolic effects of general anaesthesia during spontaneous breathing, controlled breathing, mild hypoxia and mild hypercarbia. Canad. Anaesth. Soc. J.13: 130 (1966).PubMedCrossRefGoogle Scholar
  33. 33.
    Dobkin, A.B., Byles, P.H., &Neville, J.F., Jr. Neuroendocrine and metabolic effects of general anaesthesia and graded haemorrhage. Canad. Anaesth. Soc. J.13: 453 (1966).PubMedCrossRefGoogle Scholar
  34. 34.
    Dobkin, A.B., Byles, P.H., Africa, B.F., &Neville, J.F., Jr. Neuroendocrine and metabolic effects of general anaesthesia associated with acute hypoxia and acute hypercarbia. Canad. Anaesth. Soc. J.14: 422 (1967).CrossRefGoogle Scholar
  35. 35.
    Byles, P.H., Dobkin, A.B., Ferguson, J.H., &Levy, A.A. Forane (Compound 469). Crossover comparison with enflurane (Ēthrane), halothane and methoxyflurane in dogs. Canad. Anaesth. Soc. J.18: 376 (1971).PubMedGoogle Scholar
  36. 36.
    Byles, P.H., Dobkin, A.B., &Jones, D.B. Forane (Compound 469). 3. Comparative effects of prolonged anaesthesia on mature beagle dogs and young rhesus monkeys. Canad. Anaesth. Soc. J.18: 397 (1971).PubMedCrossRefGoogle Scholar

Copyright information

© Canadian Anesthesiologists 1973

Authors and Affiliations

  • Allen B. Dobkin
  • Ashley A. Levy
    • 1
  1. 1.Department of Anesthesiology, State University HospitalState University of New York, Upstate Medical CenterSyracuseU.S.A.

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