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Anaesthetic dosage in thiopental-curare-nitrous oxide anaesthesia, using a thiopental-curare mixture

  • Michael KeéRi-Szántó
Article
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Summary

  1. 1

    Analysis of 86 casesin which a thiopental-curare mixture (Baird’s solution) was used, and a comparison with data obtained by others who administered the drugs separately, indicate that use of the mixture does not result in an increase of the dosage of either agent

     
  2. 2.

    Time-dose curves are presented to show that a definite curvilinear relationship exists between drug-utilization and the duration of anaesthesia.

     
  3. 3

    In cases lasting over 45 minutes intubation will not increase the anaesthetic consumption.

     

Keywords

Thiopental CANADIAN Anaesthetist Oxide Anaesthesia Anaesthetic Dosage Cent Nitrous Oxide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

RéSUMé

On a déterminé les besoins anesthésiques de 86 malades soumis à l’anesthésie au thiopental-curare (la solution de Baird). On a découvert qu’il existait une relation curvihgne très nette entre l’utilisation de & drogue et le temps d’anes thésie. La comparaison des présents énoncés avec ceux d’autres chercheurs qui ont administré le thiopental et le curare séparément, rnais selon la même technique, mdique qu’on a conservé le flexibilité de la technique en employant le mélange standard et qu’on pourrait réahser une certaine économie de curare. Les. résultats montrent aussi que, dans les interventions d’une durée supérieure à 45 minutes, l’intubation naccroit pas les besoins anesthésiques totaux du malade moven.

References

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    Beecher, H. K. Principles, Problems and Practices of Anesthesia in Thoracic Surgery 1st ed., Springfield, Ill. C C Thomas (1952).Google Scholar
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    Collins, J. V. Anesthesiology 1st ed, Philadelphia Lea & Ferbiger (1952).Google Scholar
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    Baird, J. W., Johnson, W R &VanBergen, F H. Peniothal-Curare Solution A Preliminary Report and Analysis of its Use in 150 Cases. Anesthesiology9: 141 (1948)PubMedCrossRefGoogle Scholar
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    Richardson, C H. An Introduction to Statistical Analysis. Revised ed, New York. Harcourt, Brace & Co (1944)Google Scholar
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    Buckley, J. J, VanBergen, F H, Dobkin, A B, Brown, E B Jr,Mijller, F A &Varco, R. L. Postanesthetic Hypotension following Cyclopropane Its Relationship to Hyperkapnia. Anesthesiology14. 26 (1953)CrossRefGoogle Scholar
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    Dundee, J. W. The Influence of Controlled Respiration on Dosage of Thiopentone and d-Tubocuranne Chloride required for Abdominal Surgery. Brit. M J, Oct.25: 893 (1952).CrossRefGoogle Scholar

Copyright information

© Canadian Anesthesiologists 1955

Authors and Affiliations

  • Michael KeéRi-Szántó
    • 1
  1. 1.Division of AnaesthesiologyUniversity of Minnesota HospitalsMinneapolis 14

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