Inhibition of peptic activity in the treatment of peptic ulcer
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Summary and conclusion
Calcium carbonate and aluminum hydroxide preparation, magnesium hydroxide and sodium lauryl sulfate caused decreased peptic activity simultaneously with a rise in the pH.
Calcium carbonate, the aluminum hydroxide preparation and magnesium hydroxide caused more marked peptic inhibition than sodium lauryl sulfate.
In our studies we were unable to confirm the reported observations that sodium lauryl sulfate inhibits peptic activity in the presence of an unaltered pH.
Clinical use of sodium lauryl sulfate on a small number of patients on the usual dietary peptic ulcer management failed to reveal any superiority of this medication over some of the other medications used.
KeywordsPeptic Ulcer Aluminum Hydroxide Test Meal Sodium Lauryl Sulfate Magnesium Hydroxide
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