Conclusion
La TEP apparaît aujourd'hui comme une technique incontournable en cancérologie. Associée aux autres modalités d'imagerie, elle permet des bilans très précis dans la stadification initiale et les récurrences d'un grand nombre d'affections malignes. Sur le plan médico-économique, elle permettra probablement, comme le démontre un certain nombre de publications américaines, des économies substantielles obtenues essentiellement en évitant des chirurgies inutiles. En cas de chirurgie possible, on pourra utiliser des sondes per-opératoires dans le but d'obtenir une exérèse complète.
L'importance de la fixation du18FDG étant directement liée à l'évolutivité des lésions, la TEP apparaît également comme un excellent moyen de contrôle de l'efficacité d'une chimiothérapie et ceci dès la première ou deuxième cure [25].
Références
AKHURST T., LARSON S.M.—Positron emission tomography imaging of colorectal cancer.Semin. Oncol., 1999 Oct.,26 (5), 577–583.
BENDER H., BANGARD N., METTEN N., BANGARD M., MEZGER J., SCHOMBURG A.—Possible role of FDG-PET in the early prediction of therapy outcome in liver metastases of colorectal cancer.Hybridoma, 1999 Feb.,18(1), 87–91.
BENYOUNES H., SMITH F.W., CAMPBELL C., EVANS N.T., NORTON M.Y., MIKECZ P., HEYS S.D., BRUCE D., EREMIN O., SHARP P.F.—Superimposition of PET images using 18F-fluorodeoxyglucose with magnetic resonance images in patients with pancreatic carcinoma.Nucl. Med. Commun., 1995 Jul.,16(7), 575–580.
BOYKIN K.N., ZIBARI G.B., LILIEN D.L., McMILLAN R.W., AULTMAN D.F., McDONALD J.C.—The use of FDG-positron emission tomography for the evaluation of colorectal metastases of the liver.Am. Surg., 1999 Dec.,65 (12), 1183–1185.
COMBS C.S., BRUNT E.M., LOWE V.J., WOLVERSON M.K., SOLOMON H., COLLINS B.T., DI BISCEGLIE A.M. —Positron emission tomography scanning in the evaluation of hepatocellular carcinoma.J. Hepatol., 2000 May,32 (5), 792–797.
DELBEKE D., ROSE D.M., CHAPMAN W.C., PINSON C.W., WRIGHT J.K., BEAUCHAMP R.D., SHYR Y., LEACH S.D.—Optimal interpretation of FDG PET in the diagnosis, staging and management of pancreatic carcinoma.J. Nucl. Med., 1999 Nov,40(11), 1784–1791.
DELBEKE D., MARTIN W.H., SANDLER M.P., CHAPMAN W.C., WRIGHT J.K.J.R., PINSON C.W.—Evaluation of benign vs malignant hepatic lesions with positron emission tomography.Arch. Surg. 1998 May,133 (5), 510–515; discussion, 510–516.
FLAMEN P., STROOBANTS S., VAN CUTSEM E., DUPONT P., BORMANS G., DE VADDER N., PENNINCKX F., VAN HOE L., MORTELMANS L.—Additional value of whole-body positron emission tomography with fluorine-18-2-fluoro-2-deoxy-D-glucose in recurrent colorectal cancer.J. Clin. Oncol., 1999 Mar,17(3), 894–901.
FLANAGAN F.L., DEHDASHTI F., SIEGEL B.A., TRASK D.D., SUNDARESAN S.R., PATTERSON G.A., COOPER J.D.—Staging of esophageal cancer with 18F-fluorodeoxyglucose positron emission tomography.AJR Am. J. Roentgenol., 1997 Feb.,168(2), 417–424.
FONG Y., SALDINGER P.F., AKHURST T., MACAPINLAC H., YEUNG H., FINN R.D., COHEN A., KEMENY N., BLUMGART L.H., LARSON S.M.—Utility of 18F-FDG positron emission tomography scanning on selection of patients for resection of hepatic colorectal metastases.Am. J. Surg., 1999 Oct.,178(4), 282–287.
FRANKE C., KLAPDOR R., MEYERHOFF K., SCHAUMAN M. —18-FDG positron emission tomography of the pancreas: diagnostic benefit in the follow-up of pancreatic carcinoma.Anticancer Res., 1999 Jul.–Aug.,19(4A), 2437–2442.
HO C.L., DEHDASHTI F., GRIFFETH L.K., BUSE P.E., BALFE D.M., SIEGEL B.A.—FDG-PET evaluation of indeterminate pancreatic masses.J. Comput. Assist. Tomogr., 1996 May–Jun,20(3), 363–369.
HUSTINX R., PAULUS P., DAENEN F., DETROZ B., HONORE P., JACQUET N., RIGO P.—Role of positron emission tomography is the evaluation of digestive tract tumors.Rev. Med. Liege, 1999 Dec.,54(12), 925–930.
GUPTA N., BRADFIELD H.—Role of positron emission tomography scanning in evaluating gastrointestinal neoplasms.Semin. Nucl. Med., 1996 Jan.,26(1), 65–73.
IMDAHL A., REINHARDT M.J., NITZSCHE E.U., MIX M., DINGELDEY A., EINERT A., BAIER P., FARTHMANN E.H.—Impact of 18F-FDG-positron emission tomography for decision making in colorectal cancer recurrences.Langenbecks Arch. Surg., 2000 Mar,385(2), 129–134
INOKUMA T., TAMAKI N., TORIZUKA T., MAGATA Y., FUJII M., YONEKURA Y., KAJIYAMA T., OHSHIO G., IMAMURA M., KONISHI—Evaluation of pancreatic tumors with positron emission tomography and F-18 fluorodeoxyglucose: comparison with CT and US.J. Radiology, 1995 May,195(2), 345–352.
IWATA Y., SHIOMI S., SASAKI N., JOMURA H., NISHIGUCHI S., SEKI S., KAWABE J., OCHI H.—Clinical usefulness of positron emission tomography with fluorine-18-fluorodeoxyglucose in the diagnosis of liver tumors.Ann. Nucl. Med., 2000 Apr,14(2), 121–126.
KOLE A.C., PLUKKER J.T., NIEWEG O.E.—Positron emission tomography for staging of oesophageal and gastroesophageal malignancy.Br. J. Cancer, 1998 Aug.,78(4), 521–527.
LANDONI C., GIANOLLI L., LUCIGNANI G., MAGNANI P., SAVI A., TRAVAINI L., GILARDI M.C., FAZIO F.— Comparison of dual-head coincidence PET versus ring PET in tumor patients.J. Nucl. Med., 1999 Oct,40(10), 1617–1622.
LONNEUX M., SIBOMANA M., PAUWELS S., GREGOIRE V. —Current data and perspectives on positron emission tomography oncology-radiotherapy.Cancer Radiother., 1999 Jul.–Aug.,3(4), 275–288.
PHELPS M.E.—PET: the merging of biology and imaging into molecular imaging.J. Nucl. Med., 2000 Aprl.,41(4), 661–681.
RANKIN S.C., TAYLOR H., COOK G.J., MASON R.— Computed tomography and positron emission tomography in the pre-operative staging of oesophageal carcinoma.Clin. Radiol., 1998 Sep.,53(9), 659–665.
RESKE S.N., GRILLENBERGER K.G., GLATTING G., PORT M., HILDEBRANDT M., GANSAUGE F., BEGER H.G.—Overexpression of glucose transporter 1 and increased FDG uptake in pancreatic carcinoma.J. Nucl. Med., 1997 Sep.,38(9), 1344–1348.
SCHRODER O., TROJAN J., ZEUZEM S., BAUM R.P.— Limited value of fluorine-18-fluorodeoxyglucose PET for the differential diagnosis of focal liver lesions in patients with chronic hepatitis C virus infection.Nuklearmedizin, 1998,37 (8), 279–285.
STRAUSS L.G.—Positron Emission Tomography: Current Role for Diagnosis and Therapy Monitoring in Oncology.Oncologist, 1997,2(6), 381–388.
TORIZUKA T., TAMAKI N., INOKUMA T., MAGATA Y., SASAYAMA S., YONEKURA Y., TANAKA A., YAMAOKA Y., YAMAMOTO K., KONISHI J.—In vivo assessment of glucose metabolism in hepatocellular carcinoma with FDG-PET.J. Nucl. Med., 1995 Oct,36(10), 1811–1817.
TORIZUKA T., TAMAKI N., INOKUMA T., MAGATA Y., YONEKURA Y., TANAKA A., YAMAOKA Y., YAMAMOTO K., KONISHI J.—Value of fluorine-18-FDG-PET to monitor hepatocellular carcinoma after interventional therapy.J. Nucl. Med., 1994 Dec.,35(12), 1965–1969.
TROJAN J., SCHROEDER O., RAEDLE J., BAUM R.P., HERRMANN G., JACOBI V., ZEUZEM S.—Fluorine-18 FDG positron emission tomography for imaging of hepatocellular carcinoma.Am. J. Gastroenterol., 1999 Nov,94(11), 3314–3319.
ZIMNY M., BARES R., FASS J., ADAM G., CREMERIUS U., DOHMEN B., KLEVER P., SABRI O., SCHUMPELICK V., BUELL U.—Fluorine-18 fluorodeoxyglucose positron emission tomography in the differential diagnosis of pancreatic carcinoma: a report of 106 cases.Eur. J. Nucl. Med., 1997 Jun,24(6), 678–682.
Author information
Authors and Affiliations
About this article
Cite this article
Monteil, J., Verbeke, S., Ducloux, T. et al. Place de la tomographie d'émission à positron en gastro-entérologie. Acta Endosc 30 (Suppl 2), 377–381 (2000). https://doi.org/10.1007/BF03017982
Issue Date:
DOI: https://doi.org/10.1007/BF03017982