Summary
Cortisone and A C T H act on every tissue of the organism by a mechanism which is still unknown; therefore, they must be used with extreme care The cases must be meticulously selected and the dose must be adjusted for each case so that it will bring about the best result with the least side effects. The evaluation of these results is also difficult
On the whole, we feel that it is better to use A.C T H. than Cortisone, because in this way at least the post-cortisone hypotrophia and hypoplasia of the adrenal glands, so dangerous to “stress,” can be completely avoided The treatment for patients undergoing adrenal surgery is outlined
Résumé
La Cortisone et l’A.C.T.H. agissent sur tous les tissus de l’organisme par un mécanisme encore inconnu. C’’est pourquoi, on doit les employer qu’avec très grandes précautions. Les cas doivent être choisis de façon méticuleuse et la dose doit être ajustée pour chaque cas de tel sorte qu’elle produise le meilleur r’sultat possible avec le moms d’effets secondaires. L’évaluation des résultats est aussi difficile.
A tout considérer, nous croyons qu’il vaut mieux employer l’A.C.T.H. que la Cortisone parce que de cette facon au nioins, on évite les esffets d’hypotrophie et d’hypoplasie des surrénales si dangereuses sous le “stress.” On donne le traitement à siuvre chez les patients qui doivent avoir une interventionésur les surrénales.
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Romagnoli, A.G.F. Cortisone and anaesthesia. Canad Anaes Soc J 2, 255–262 (1955). https://doi.org/10.1007/BF03016168
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DOI: https://doi.org/10.1007/BF03016168