Experimental studies of the central nervous system related to anaesthesia: IV. effects of pentobarbital placement in caudate nucleus
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Deep sedation results, in cats, when pentobarbital is placed in the head of caudate nucleus through precise stereotaxically implanted recording cannulae. This sedation persists in the presence of a variety of auditory stimuli, as observed by a lack of behavioural arousal and alertness and the persistence of an eeg and subcortical correlate of deactivation.
Following the application of pentobarbital into amygdala, hippocampus, ventro-postero-lateral thalamic nucleus, centro-median thalamic nucleus, and posterior hypothalamic nuclei, there was no persistent behavioural or electroencephalographic evidence of sedation in the presence of repetitive stimuli.
KeywordsPentobarbital Auditory Stimulus Caudate Nucleus Thalamic Nucleus Electrical Recording
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