Summary
Deep sedation results, in cats, when pentobarbital is placed in the head of caudate nucleus through precise stereotaxically implanted recording cannulae. This sedation persists in the presence of a variety of auditory stimuli, as observed by a lack of behavioural arousal and alertness and the persistence of an eeg and subcortical correlate of deactivation.
Following the application of pentobarbital into amygdala, hippocampus, ventro-postero-lateral thalamic nucleus, centro-median thalamic nucleus, and posterior hypothalamic nuclei, there was no persistent behavioural or electroencephalographic evidence of sedation in the presence of repetitive stimuli.
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Leighton, K.M., Jenkins, L.C. Experimental studies of the central nervous system related to anaesthesia: IV. effects of pentobarbital placement in caudate nucleus. Canad. Anaesth. Soc. J. 17, 112–118 (1970). https://doi.org/10.1007/BF03004661
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DOI: https://doi.org/10.1007/BF03004661