The American Journal of Digestive Diseases

, Volume 4, Issue 11, pp 742–752 | Cite as

Intubation studies of the human small intestine: VII. Factors concerned in absorption of glucose from the jejunum and ileum

  • W. Osler Abbott
  • Walter G. Karr
  • T. Grier Miller


1. Within wide limits the jejunal and ileal contents usually contain 5 per cent glucose or less without regard to the volume or concentration of the glucose solution ingested.

2. As the stomach evacuates a concentrated glucose meal the duodenal and upper jejunal contents, although markedly diluted, usually are found to be hypertonic with regard to the body fluids, while with the rise and fall in the glucose content that may occur in the lower small intestine isotonicity is maintained.

3. If hypertonic solutions are placed in the small intestine the rise in volume and fall in concentration proceeds with great rapidity.

4. The propulsive activity of the small intestine increases with the concentration of glucose above 5.4 per cent in the gut contents.

5. Using solutions containing glucose in concentrations naturally occurring in the jejunum and ileum, (5 per cent or under), the rate of absorption is found to increase with the concentration.


Small Intestine Hypertonic Solution Glucose Solution Human Small Intestine Cent Glucose 
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Copyright information

© Springer-Verlag 1937

Authors and Affiliations

  • W. Osler Abbott
    • 1
    • 2
  • Walter G. Karr
    • 1
  • T. Grier Miller
    • 1
  1. 1.Philadelphia
  2. 2.F. M. Kirby Fellow in Surgical PhysiologUSA

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