Quantum description of synaptic nervous function

The phenomenological status of the conditional reflex
  • James P. Isaacs
  • John C. Lamb


A profound problem exists in formulating a mode for description of biological phenomena which is unified with that for chemistry and physics. A similar problem occurred historically with respect to chemical phenomena and physics. Section I of this paper is a sketch of how the resolution of conceptual dualism between physics and chemistry came about by the application of quantum description. The end of Section I and all of Section II is an exercise concerned with neurophysiology and psychobiology at the level of synaptic function which serves as an example of how resolution of conceptual dualism betweephysics and biology is also possible by application of quantum description. Coincidentally, the phenomenological status of the conditional reflex is clarified by this exercise.


Quantum Theory Conditional Reflex Turing Machine Molecular Motion Spatial Summation 
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  1. Bucy, P. C.: Conditional reflexes, sleep.In C. H. Best and N. B. Taylor, (Eds.):The Physiological Basis of Medical Practice, 7th ed. Baltimore, Williams and Wilkins, 1961; p.p. 1261–1275.Google Scholar
  2. Gantt, W. H.: Factors involved in the development of pathological behavior: schizokinesis and autokinesis.Perspet. Biol. Med.,5:473–482, 1962.Google Scholar
  3. Gantt, W. H.: Reflexology, schizokinesis and autokinesis.Cond. Reflex,1:57–68, 1966.Google Scholar
  4. Goppert Mayer, M.: Two-quantum processes.Ann. Physik.,9:273–279, 1931.CrossRefGoogle Scholar
  5. Haber, R. N., and Standing, L. G.: Direct measures of short-term visual storage.Q. J. Exp. Psychol.,21:43–54, 1969.PubMedCrossRefGoogle Scholar
  6. Isaacs, J. P., and Lamb, J. C.:Complimentarity in Biology. Baltimore, The Johns Hopkins Press, 1969; pp. 153–157.Google Scholar
  7. Heisenberg, W.:Physics and Philosophy. New York, Harper, 1962; 180–186.Google Scholar
  8. Jammer, M.:The Conceptual Development of Quantum Mechanics. New York, McGraw Hill, 1966; pp. 89–109, 191–195, 204–223, and 281–322.Google Scholar
  9. Kaiser, W., and Garrett, C. G. B.: Two-photon excitation in CaF2:Eu2+.Physiol. Rev. Letters,7:229–231, 1961.CrossRefGoogle Scholar
  10. Kandel, E. R., and Spencer, W. A.: Cellular neurophysiological approaches in the study of learning.Physiol. Rev.,48:65–134, 1968.PubMedGoogle Scholar
  11. Kristofferson, A. B.: Successiveness discrimination as a two-state, quantal process.Science,158:1337–1339, 1967.PubMedCrossRefGoogle Scholar
  12. Lamb, J. C., and Isaacs, J. P.: Indeterminacy, the synapse, the mnemic microstate, and the psyche.Cond. Reflex,4:1–5, 1969.PubMedGoogle Scholar
  13. Lamb, J. C., and Isaacs, J. P.: Quantization of molecular motion at the synapse and its consequences as contrasted with the generalized Turing machine.Cond. Reflex. 7:115, 1972.PubMedGoogle Scholar
  14. McLennan, H.:Synaptic Transmission. Philadelphia, Saunders, 1970.Google Scholar
  15. Pavlov, I. P.:Conditional Reflexes. Oxford Univ. Press, 1928.Google Scholar
  16. Richtmyer, F. K., and Kennard, E. H.:Introduction to Modern Physics. New York, McGraw-Hill, 1947; pp. 280–282.Google Scholar
  17. von Bekesy, G.: Auditory backward inhibition in concert halls.Science,171: 529–536, 1971.CrossRefGoogle Scholar
  18. Wachtel, H., and Kandel, E. R.: A direct synaptic connection mediating both excitation and inhibition.Science,158:1206–1208, 1967.PubMedCrossRefGoogle Scholar
  19. Weisskopf, V. F.: Quantum theory and elementary particles.Science,149:1181–1189, 1965.PubMedCrossRefGoogle Scholar

Copyright information

© Springer 1972

Authors and Affiliations

  • James P. Isaacs
    • 1
  • John C. Lamb
    • 1
  1. 1.Church Home and HospitalThe Johns Hopkins University School of MedicineBaltimore

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