The American Journal of Digestive Diseases

, Volume 8, Issue 2, pp 39–42 | Cite as

The treatment of massive gastro-duodenal hemorrhage by the continuous administration of colloidal aluminum hydroxide (A Report of 144 Cases)

  • Edward E. Woldman

Summary and Conclusions

One hundred and forty-four patients with massive hemorrhages resulting from gastric or duodenal ulcer were treated by the continuous administration of colloidal aluminum hydroxide. In this series, there were three deaths, or a mortality rate of 2 per cent, as contrasted to a mortality rate of 28 per cent during a similar period at the same hospital, preceding the inauguration of this form of medical treatment. The continuous administration of colloidal aluminum hydroxide in massive gastric hemorrhage presents certain advantages over other methods of treatment:
  1. 1.

    It is a harmless, non-absorbable astringent which is capable of hastening the formation of a clot.

  2. 2.

    By virtue of its antacid properties it can prevent the digestion of the clot by continuously neutralizing the excess acid in the stomach, without danger of alkalosis.

  3. 3.

    Because it is a gelatinous substance, it has the additional advantage of mechanically protecting the lesion.

  4. 4.

    As the result of continuous administration of colloidal aluminum hydroxide, both day and night, the delicate granulation tissue formed in the process of healing is not destroyed by the accumulation of acid during the night, and thus the lesion is permitted to heal.



Peptic Ulcer Duodenal Ulcer Aluminum Hydroxide Massive Hemorrhage Continuous Administration 
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Copyright information

© Springer-Verlag 1941

Authors and Affiliations

  • Edward E. Woldman
    • 1
  1. 1.Department of Gastro-EnterologySt. Luke’s HospitalCleveland

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