Production of peptic ulcers in rats and mice by diets deficient in protein

  • Frederick Hoelzel
  • Esther Da Costa


Ulceration of the prostomach and main stomach of rats and mice and ulceration of the duodenum of mice but not of rats was found to occur as a result of starvation or diets deficient in protein or in essential amino-acids.

Ulceration thus produced is regarded as objective evidence of protein-hunger or amino-acid-hunger which has been carried to a pathologic extreme.


Bran Duodenal Ulcer Gastric Ulcer Obstructive Jaundice Main Stomach 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 1937

Authors and Affiliations

  • Frederick Hoelzel
    • 1
  • Esther Da Costa
    • 1
  1. 1.Chicago

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