The American Journal of Digestive Diseases

, Volume 3, Issue 2, pp 102–107 | Cite as

The effects on the gastric juice of man of six weeks’ Deprivation of vitamin B1

  • Walter C. Alvarez
  • Frederick Pilcher
  • Mary A. Foley
  • Annette Mayer
  • Arnold E. Osterberg


Gastric Juice Mayo Clinic Normal Diet Free Acidity Gastric Secretion 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Danysz-Michel and Koskowski, W.: Etude de quelques fonctions digestive chez lez pigeons normaux, nourris au riz poli et en inanition.Compt.-rend. Acad. d. sc., 175:54–56, July 3, 1922.Google Scholar
  2. 2.
    Farnum, Martha B.: Gastric secretion in experimental beriberi in the dog.Arch. Int. Med., 37:212–216, Feb., 1926.Google Scholar
  3. 3.
    Gildea, E. F., Kattwinkel, E. E., and Castle, W. B.: Experimental combined system disease.New England Jour. Med., 202:523–527, March 13, 1930.Google Scholar
  4. 4.
    Cowgill, G. R., and Gilman, Alfred: Physiology of vitamins. XXIII. The effect of lack of the vitamin B complex on the secretion of gastric juice in dogs with gastric pouches.Arch. Int. Med., 53:58–70, Jan., 1934.Google Scholar
  5. 5.
    Webster, D. R., and Armour, J. C.: Vitamin B complex and gastric secretion.Proc. Soc. Exper. Biol. and Med., 31:463–464, Jan., 1934.Google Scholar
  6. 6.
    Komarov, S. A.: Presence of vitamin B1 in the gastric juice.Proc. Soc. Exper. Biol. and Med., 32:398–400, Nov., 1934.Google Scholar
  7. 7.
    Sure, Barnett, and Thatcher, H. S.: Experimental production of gastric ulcers in the albino rat, as a resu’t of vitamin G deficiency: also as a result of the specific influence of vitamin B deficiency.South. Med. Jour., 27:634–636, July, 1934.CrossRefGoogle Scholar
  8. 8.
    Dalldorf, Gilbert, and Kellogg, Minerva: Incidence of gastric ulcer in albino rats fed diets deficient in vitamin B (B1).Jour. Exper. Med., 56:391–398, Sept. 1, 1932.CrossRefGoogle Scholar
  9. 9.
    Kitimura, S., and Shimazono, J.: Ueber das Verhalten des Magensaftes bei beriberi.Internat. Beitr. z. Path. u. Therap. der Ernährungsstör., Stoffwechs. u. Verdauungskrankh., 4:30–43, 1912.Google Scholar
  10. 10.
    Ohta, Kohshi, and Izumita, Tomotake: Zur Kenntnis der Funktionsanomalien des Verdauungskanals bei der Säuglings-Beriberi, Uber die Sekretinsanomalie des Magens bei der Säuglings-Beriberi.Jchrb. f. Kinderh., 128:161–198, 1930.Google Scholar
  11. 11.
    Vedder, E. B.: Beriberi. New York, William Wood & Company, 427 pp., 1913.Google Scholar
  12. 12.
    Cowgill, G. R.: Vitamin B: clinical aspects.Internat. Clin., 4:54–84, Dec., 1934.Google Scholar
  13. 13.
    Middleton, E. M.: Quoted by Cowgill (12). Cowgill, G. R.:Google Scholar
  14. 14.
    Elsom, Katherine O.: Experimental study of clinical vitamin B deficiency.Jour. Clin. Invest., 14:40–51, Jan., 1935.CrossRefGoogle Scholar
  15. 15.
    Cowgill, G. R.: The vitamin B requirement of man. New Haven, Yale University Press, 261 pp., 1934.Google Scholar
  16. 16.
    Osterberg, A. E., Vanzant, Frances R., and Alvarez, W. C.: Studies of gastric pepsin. I. Methods of measurement and factors which influence it.Jour. Clin. Invest., 12:551–556, May, 1933.CrossRefGoogle Scholar
  17. 17.
    Vanzant, Frances R.: The effect of injection of nonspecific protein on the pain of ulcer and on gastric secretion.Proc. Staff Meetings of Mayo Clinic, 6:745–747. Dec. 16, 1931.Google Scholar
  18. 18.
    Vanzant, Frances R., and Snell, A. M.: The effect of injection of nonspecific protein on the pain of ulcer and on gastric secretion: a clinical and experimental study.Jour. Clin. Invest., 11:647–659, July, 1932.CrossRefGoogle Scholar
  19. 19.
    Vanzant, Frances R., and Alvarez, W. C.: What is the value of one gastric analysis? A study of the daily variations in the gastric acidity of two normal persons.Proc. Staff Meetings of Mayo Clinic, 6:419–422, July 15, 1931.Google Scholar
  20. 20.
    Vedder, E. B.: Beriberi and epidemic edema. Oxford medicine. Vol. IV, part 2, p. 289, 1920.Google Scholar
  21. 21.
    Cartland, G. F., and Koch, F. C.: Diet proteins and vitamins as related to hemoglobin production in the rat.Am. Jour. Physiol., 87:249–231, Nov., 1928.Google Scholar
  22. 22.
    Strauss, M. B., and Castle, W. B.: The nature of the extrinsic factor of the deficiency state in primary pernicious araemia and in related macrocytic anaemias.New England Jour. Med., 207: 55–59, July 14, 1932.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1936

Authors and Affiliations

  • Walter C. Alvarez
    • 1
    • 2
  • Frederick Pilcher
    • 1
    • 3
  • Mary A. Foley
    • 1
    • 4
  • Annette Mayer
    • 1
    • 5
  • Arnold E. Osterberg
    • 1
    • 6
  1. 1.Rochester
  2. 2.Division of MedicineThe Mayo ClinicUSA
  3. 3.The Mayo FoundationUSA
  4. 4.Division of Medicine (Dietetics)The Mayo ClinicUSA
  5. 5.Kahler CorporationUSA
  6. 6.Section on BiochemistryThe Mayo FoundationUSA

Personalised recommendations