The American Journal of Digestive Diseases

, Volume 1, Issue 2, pp 120–123 | Cite as

Gastro-intestinal studies

IV. The Relation of pH to the pepsin and rennin content of the gastric juice
  • O. M. Helmer
  • Paul J. Fouts
  • L. G. Zerfas
Experimental Physiology

Summary and Conclusions

1. The presence of pepsin and rennin in the gastric juice cannot be demonstrated unless the pH of the sample is 7.0 or below; however, the height of the secretion of these enzymes does not necessarily depend upon the amount of acid secreted.

2. The importance of titrating to neutrality with phenol red as an indicator is pointed out.

3. It is suggested that the term “achylia gastrica,” in contrast to the term “anacidity,” be reserved for that condition in which not only is there an absence of acid, pepsin, and rennin, but also of the intrinsic factor of Castle.


Free Acid Pernicious Anemia Jejunal Ulcer Free Hydrochloric Acid Histamine Stimulation 


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Copyright information

© Springer-Verlag 1934

Authors and Affiliations

  • O. M. Helmer
    • 1
  • Paul J. Fouts
    • 1
  • L. G. Zerfas
    • 1
  1. 1.Indianapolis

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