Basal secretion of Pavlov pouch dogs as influenced by oxygen want

  • Edward J. Van Liere
  • Paul E. Vaughan


The chlorides, acids and pH of the basal secretion of the Pavlov pouch are not appreciably affected by oxygen want within ranges compatible with consciousness in the unacclimatized dog.

The volume of basal secretion is not affected by moderate ranges of oxygen want as much as is the secretion provoked by food. The more severe degrees of oxygen want, however, depress the basal secretion the same as it does the secretion caused by the stimulating action of food.

The work suggests that the basal secretion of the gastric glands has a low oxygen requirement.

Finally, it is of clinical interest to know that even moderately severe degrees of oxygen want have no appreciable affect on the basal gastric secretion.


Gastric Juice Clinical Interest Moderate Range Gastric Gland Severe Degree 


  1. 1.
    Pickett, A. D. and Van Liere, E. J.:Am. J. Physiol., 127:637, 1939.Google Scholar
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    Van Liere, E. J.:J. Lab. Clin. Med., 21:963, 1936.Google Scholar
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    Fischer, R. A.: Statistical Methods for Research Workers. Oliver and Boyd, London, 4th ed., 1932.Google Scholar

Copyright information

© Springer-Verlag 1941

Authors and Affiliations

  • Edward J. Van Liere
    • 1
  • Paul E. Vaughan
    • 1
  1. 1.Department of Physiology, School of MedicineWest Virginia UniversityMorgantown

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