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Chinese Journal of Cancer Research

, Volume 2, Issue 4, pp 60–63 | Cite as

Tegafur plus MMC or ACNU in the treatment of advanced gastric cancer-a pilot study

  • Zhang Darong 
  • Xiao Shudong 
  • Jiang Shaoji 
  • Minoru Kurihara 
Clinical Observations
  • 12 Downloads

Abstract

Twenty four cases of advanced gastric cancer were divided into two groups according to the general condition of the patients (PS 0–2 and 3–4), further subdivided into localized abdominal form, liver metastatic form, ascitic form and distant metastatic form. These patients were allocated randomly into Regimen A or B. Regimen A: Tegafur 600 mg daily and Mitomycin C (MMC) 5 mg/m2/1–2 weeks. Regimen B: Tegafur 600 mg daily and ACNU (Nimustine, water-soluble Nitrosourea) 60 mg/week for 2 weeks. After a course of ACNU, it was with drawn for 4 weeks and then resumed again. The response rate of Regimen A was 3/11 (27%), that of Regimen B was 3/13 (23%).

Keywords

Gastric Cancer Mitomycin Advanced Gastric Cancer Tegafur Barium Meal 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Chinese Journal of Cancer Research 1990

Authors and Affiliations

  • Zhang Darong 
    • 1
  • Xiao Shudong 
    • 1
  • Jiang Shaoji 
    • 1
  • Minoru Kurihara 
    • 1
    • 2
  1. 1.Shanghai Institute of Digestive DiseaseChina
  2. 2.Department of Internal Medicine, Toyosu HospitalShowa UniversityTokyoJapan

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