The American Journal of Digestive Diseases

, Volume 9, Issue 6, pp 202–205 | Cite as

The influence of certain commonly used drugs on the rate of gastric emptying in the normal human subject as determined by an intubation technique

(Atropine, Morphine, Benzedrine, Prostigmine, Nitroglycerine, Syntropan, Mecholyl, Ergotamine Tartrate and Sodium Bicarbonate)
  • Jarrett H Folley
  • W. Osler Abbott


The gastric emptying curve of five normal human subjects as obtained by repeated aspiration, measurement and reinjection of a test solution was essentially unaltered by clinical doses of atropine sulphate, amphetamine sulphate, prostigmine, nitroglycerine, “Syntropan,” acetyl-B-methylcholine chloride, ergotamine tartrate or sodium bicarbonate. Morphine sulphate produced a delayed inhibition of gastric emptying in each of five experiments.


Cellulose Gastric Emptying Ergotamine Atropine Sulphate Normal Human Subject 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Abbott, W. O. and Pendergrass, E. P.: Intubation Studies of the Human Small Intestine: V. The Motor Effects of Single Clinical Doses of Morphine Sulphate in Normal Subjects.Am. J. Roent., 35:289–299, March, 1936.Google Scholar

Copyright information

© Springer-Verlag 1942

Authors and Affiliations

  • Jarrett H Folley
    • 1
  • W. Osler Abbott
    • 1
  1. 1.Gastrointestinal Section (Kinsey-Thomas Foundation) of the Medical ClinicHospital of the University of PennsylvaniaPennsylvania

Personalised recommendations