The influence of certain commonly used drugs on the rate of gastric emptying in the normal human subject as determined by an intubation technique
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The gastric emptying curve of five normal human subjects as obtained by repeated aspiration, measurement and reinjection of a test solution was essentially unaltered by clinical doses of atropine sulphate, amphetamine sulphate, prostigmine, nitroglycerine, “Syntropan,” acetyl-B-methylcholine chloride, ergotamine tartrate or sodium bicarbonate. Morphine sulphate produced a delayed inhibition of gastric emptying in each of five experiments.
KeywordsCellulose Gastric Emptying Ergotamine Atropine Sulphate Normal Human Subject
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- 1.Abbott, W. O. and Pendergrass, E. P.: Intubation Studies of the Human Small Intestine: V. The Motor Effects of Single Clinical Doses of Morphine Sulphate in Normal Subjects.Am. J. Roent., 35:289–299, March, 1936.Google Scholar