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Chinese Journal of Cancer Research

, Volume 4, Issue 3, pp 49–54 | Cite as

Immunohistochemical study on 543 cases with monoclonal antibodies against human lung cancer

  • Wang Qinqin 
  • Jang Ping 
  • Hao Ping 
  • Meng Hua 
  • Dong Jian 
  • Cheng Xinming 
  • Zhang Kaixin 
  • Zhou Kemin 
Clinical Observations
  • 7 Downloads

Abstract

Three hybridized cell line, F-19, N-35 and SIA-2 which secrete monoclonal antibodies (McAbs) against human lung cancer have been established by using the cell fusion technique. The three cell lines have been culturedin vitro for 14 to 16 months and can produce Monoclonal Antibodies steadily. With the three monoclonal antibodies, the immunohistochemistry technique has been applied to detect different histocytes from human lung cancer, various normal or abnormal tissues and organs. The potency that the monoclonal antibodies will be applied in clinic has also been studied.

Key words

McAbs lung cancer immunohistochemistry 

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References

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    Hsu S M, et al. Use of avidin — biodin peroxidase complex ( ABC ) in immunoperoxidase technique: a comparison between ABC and unlabelled antibody (PAP) procedures. J. Histochem. Cytochem. 1981; 29:577.PubMedGoogle Scholar

Copyright information

© Chinese Journal Of Cancer Research 1992

Authors and Affiliations

  • Wang Qinqin 
    • 1
  • Jang Ping 
    • 1
  • Hao Ping 
    • 1
  • Meng Hua 
    • 1
  • Dong Jian 
    • 1
  • Cheng Xinming 
    • 1
  • Zhang Kaixin 
    • 1
  • Zhou Kemin 
    • 1
  1. 1.Yunnan Institute for Cancer ResearchKunming

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