The American Journal of Digestive Diseases

, Volume 6, Issue 4, pp 257–261 | Cite as

Chronic regional enteritis occurring in three siblings

  • Philip W. Brown
  • Charles H. Scheifley


Three siblings, two sisters and a brother, have been found to exhibit various manifestations characteristic of regional enteritis. The occurrence of this disease in three members of one family is uncommon. The great difficulties that may arise in the management of this disease are illustrated by the cases of the sisters. In the light of present knowledge, resection of the diseased portion is the therapeutic procedure of choice but a better understanding of this unusual disease may, in the future, offer a less radical treatment. We feel that enterocolitis is a late stage in the progress of regional enteritis.


Gastric Secretion Barium Enema Terminal Portion Chronic Ulcerative Colitis Hepatic Flexure 
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    Crohn, B. B., Ginzburg, Leon and Oppenheimer, G. D.: Regional Ileitis; a Pathologic and Clinical Entity.J. A. M. A., 99:1323–1329, Oct. 15, 1932.Google Scholar
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    Crohn, B. B.: The Broadening Conception of Regional Ileitis.Am. J. Digest. Die. and Nutrit., 1:97–99, April, 1934.Google Scholar
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    Pemberton, J. deJ. and Brown, P. W.: Regional Ileitis.Ann. Surg., 105:855–870, May, 1937.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1939

Authors and Affiliations

  • Philip W. Brown
    • 1
  • Charles H. Scheifley
    • 2
  1. 1.Division of MedicineThe Mayo ClinicRochester
  2. 2.Fellow in MedicineThe Mayo FoundationRochester

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