Mucociliary clearance in chronic sinusitis
Mucociliary clearance is an important defence mechanism of upper and lower respiratory tracts. Any disturbance in the mechanism leads to stagnation of secretions and secondary infection with prolonged mucociliary clearance time. The present study was undertaken to establish normal mucociliary clearance time in our region and to evaluate its diagnostic and prognostic potential in chronic sinusitis of variable duration with and without obstructive diseases.
A simple Saccharine test was done in twenty healthy individuals and fifty patients suffering from Chronic Sinusitis, before and after treatment, to know the effect of disease on mucociliary clearance.
The normal mucociliary clearance time in our region is 6.99 ± 0.26 with S.D. 1.15 and significant change in mucociliary clearance occurs in Chronic Sinusitis.
KeywordsSinusitis Chronic Sinusitis Mucociliary Clearance Inferior Turbinate Maxillary Sinusitis
Unable to display preview. Download preview PDF.
- 1.Andersen, I.;Camner, P.;Jenson, PL.: Philipson, K.;Proctol, D.F. (1974): Nasal clearance in monozygotic twins. American Review of Respiratory Diseases, 110: 301.Google Scholar
- 2.Bang, B.C.; Mukherjee, A. L; Bang, F. B. (1967): Human nasal mucus flow rates. The Johns Hopkins Medical Journal, 121:38.Google Scholar
- 3.Berg, O.H.; Bergstedt, C.; Carenfelt and Zind, M.G. (1981): Discrimination of purulent from non-purulent maxillary sinusitis: Clinical and Radiographic Diagnosis. Ann. Otol. Rhin, and Laryng., 90:272.Google Scholar
- 4.Evert, C. (1965): On the mucus flow rate in the human nose. Acta Otolaryngologica (supplement), 200(1): 61.Google Scholar
- 5.Fabricant, N.D. (1945): Scott Browns Diseases of the Ear, Nose and Throat (Eds. Ballantyne and Groves). London: Butterworths, 4th ed., Vol. 1, P. 166.Google Scholar
- 6.Golhar, S. and Arora, M. L. (1981): The effect of cryodestruction of vidian nasal branches on nasal mucus flow in vasomotor rhinitis. Indian Journal of Otolaryngology, 33 (1): 12.Google Scholar
- 9.Hilding, A. (1931): Ciliary activity and course of secretion currents of the nose. Mayo Clinic Proceedings, 6: 285.Google Scholar
- 11.Quiolan, M.; Salman, S.; Swift, D.; Wagner, H. and Proctor, D. (1969): Measurement of mucociliary function in man. American Review of Respiratory Diseases, 88: 13.Google Scholar
- 15.Wig. U.; Jindal N.K.; Goel, H.; Chawla, R. K. and Yadav, S.P.S. (1988): Nasal mucus clearance in nasal and paranasal sinus disorders. Indian Journal of Chest Dis. and All. Sci. 30(3): 177.Google Scholar