Abstract
Mucociliary clearance is an important defence mechanism of upper and lower respiratory tracts. Any disturbance in the mechanism leads to stagnation of secretions and secondary infection with prolonged mucociliary clearance time. The present study was undertaken to establish normal mucociliary clearance time in our region and to evaluate its diagnostic and prognostic potential in chronic sinusitis of variable duration with and without obstructive diseases.
A simple Saccharine test was done in twenty healthy individuals and fifty patients suffering from Chronic Sinusitis, before and after treatment, to know the effect of disease on mucociliary clearance.
The normal mucociliary clearance time in our region is 6.99 ± 0.26 with S.D. 1.15 and significant change in mucociliary clearance occurs in Chronic Sinusitis.
Similar content being viewed by others
References
Andersen, I.;Camner, P.;Jenson, PL.: Philipson, K.;Proctol, D.F. (1974): Nasal clearance in monozygotic twins. American Review of Respiratory Diseases, 110: 301.
Bang, B.C.; Mukherjee, A. L; Bang, F. B. (1967): Human nasal mucus flow rates. The Johns Hopkins Medical Journal, 121:38.
Berg, O.H.; Bergstedt, C.; Carenfelt and Zind, M.G. (1981): Discrimination of purulent from non-purulent maxillary sinusitis: Clinical and Radiographic Diagnosis. Ann. Otol. Rhin, and Laryng., 90:272.
Evert, C. (1965): On the mucus flow rate in the human nose. Acta Otolaryngologica (supplement), 200(1): 61.
Fabricant, N.D. (1945): Scott Browns Diseases of the Ear, Nose and Throat (Eds. Ballantyne and Groves). London: Butterworths, 4th ed., Vol. 1, P. 166.
Golhar, S. and Arora, M. L. (1981): The effect of cryodestruction of vidian nasal branches on nasal mucus flow in vasomotor rhinitis. Indian Journal of Otolaryngology, 33 (1): 12.
Golhar, S. (1986): Nasal mucous clearance. The Journal of Laryngology and Otology, 100:533.
Hady, M.R.A., Shehata, O. and Hasan, R. (1983): Nasal mucociliary function in different diseases of the nose. The Journal of Laryngology and Otology, 97: 497,
Hilding, A. (1931): Ciliary activity and course of secretion currents of the nose. Mayo Clinic Proceedings, 6: 285.
Puchelle, E.; Aug, F.; Pham, Q.T. and Bertrand, A. (1981): Comparison of three methods for measuring nasal mucociliary clearance in man. Acta Otolaryngologica, 91:297.
Quiolan, M.; Salman, S.; Swift, D.; Wagner, H. and Proctor, D. (1969): Measurement of mucociliary function in man. American Review of Respiratory Diseases, 88: 13.
Stanley, P.J., Wilson, R.; Greenstone, M.A.; Mackay, I.S. and Cole, P.J. (1985): Abnormal nasal mucociliary clearance in patients with rhinitis and its relationship to concomitant chest disease. British Journal of Diseases of Chest, 79: 77.
Tremble, G.E. ( 1948) Clinical observation in the movement of nasal cilia: An experimental study. The Laryngoscope, 58:206.
Vinther, B. and Elbrond, O. (1978): Nasal mucociliary function during penicillin treatment. Acta. Otolaryngol. 86: 132.
Wig. U.; Jindal N.K.; Goel, H.; Chawla, R. K. and Yadav, S.P.S. (1988): Nasal mucus clearance in nasal and paranasal sinus disorders. Indian Journal of Chest Dis. and All. Sci. 30(3): 177.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Birdi, S.M., Singh, S. & Singh, A. Mucociliary clearance in chronic sinusitis. IJO & HNS 50, 15–19 (1998). https://doi.org/10.1007/BF02996761
Issue Date:
DOI: https://doi.org/10.1007/BF02996761