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The American Journal of Digestive Diseases

, Volume 5, Issue 6, pp 373–377 | Cite as

The gastric secretory curve before and after the mann-williamson operation, and its bearing on the normal regulation of gastric acidity

  • Charles M. Wilhelmj
  • Rex W. Finegan
Article

Summary

  1. 1.

    Following the Mann-Williamson operation the acidity of the total secretions entering the stomach is much higher than before operation. During the gastric secretory curve the acidity of the secretions continues to rise and does not show the normal terminal decrease. The non-acid secretions entering the stomach are either very small in amount or absent. These changes are due to the absence of duodenal regurgitation.

     
  2. 2.

    The emptying time of the stomach is markedly increased after operation due apparently to jejunal spasm.

     
  3. 3.

    The acidity of the gastriccontents shows little change after operation.

     
  4. 4.

    Evidence is presented which indicates that the acidity of thetotal secretions (gastric plus duodenal) entering the stomach is controlled primarily by duodenal regurgitation while the acidity of the gastriccontents is controlled primarily by acid inhibition.

     

Keywords

Acid Secretion Gastric Secretion Test Meal Gastric Content Acid Chloride 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Wilhelmj, C. M., O’Brien, F. T. and Hill, F. C.:Am. Jour. Phys., 115, 5, 1936.Google Scholar
  2. 2.
    Wilhelmj, C. M., O’Brien, F. T. and Hill, F. C.:Am. Jour. Phys., 115, 429, 1936.Google Scholar
  3. 3.
    Wilhelmj, C. M., McCarthy, H. H.and Hill, F. C.:Am. Jour. Phys., 118, 766, 1937.Google Scholar
  4. 4.
    Wilhelmj, C. M., O’Brien, F. T. and Hill, F. C.:Am. Jour. Dig. Dis. and Nutrit., 3, 319, 1936.Google Scholar
  5. 5.
    Wilhelmj, C. M., Henrich, L. C. and Hill, F. C.:Am. Jour. Phys., 111, 293, 1935.Google Scholar
  6. 6.
    Matthews, W. B. and Dragstedt, L. E.:S. G. O., 55, 265, 1932.Google Scholar
  7. 7.
    Mann, F. C.: Personal Communication.Google Scholar
  8. 8.
    Wilhelmj, C. M., O’Brien, F. T., McCarthy, H. H. and Hill, F. C.:Am. Jour. Phys., 117, 79, 1936.Google Scholar
  9. 9.
    Orndorff, J. R.. Fauley, G. B. and Ivy, A. C.:Am. Jour. Dig. Dis. and Nutrit., 3, 26, 1936.Google Scholar
  10. 10.
    McCann, J. C.:Am. Jour. Phys., 89, 483, 1929;Arch. Surgery, 19, 600, 1929.Google Scholar
  11. 11.
    Bollman, J. L.: Personal Communication.Google Scholar
  12. 12.
    Ivy, A. C.: Personal Communication.Google Scholar
  13. 13.
    Wilhelmj, C. M.. Henrich, L. C. and Hill, F. C.:Am. Jour. Phys., 110, 251, 1934.Google Scholar
  14. 14.
    Hollander, F.:Jour. Biol. Chem., 104, 33. 1934.Google Scholar
  15. 15.
    Baird. M. Mc., Campbell, J. M. H. and Hern. J. R. B.:Guy’s Hospital Reports, 74, 23, 1924.Google Scholar

Copyright information

© Springer-Verlag 1938

Authors and Affiliations

  • Charles M. Wilhelmj
    • 1
  • Rex W. Finegan
    • 2
  1. 1.Omaha, Nebraska
  2. 2.Departments of Physiology and Experimental SurgeryCreighton University School of MedicineOMAHA, NEBRASKA

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