Chinese Journal of Cancer Research

, Volume 4, Issue 4, pp 40–45 | Cite as

Assay of sensitivity of cancer cell to anticancer drug in glass capillaries

  • He Zhimin 
  • Wei Liyong 
  • Peng Xiange 
Basic Investigation


A newly established human tumor clonogenecity assay - the glass capillary tube culture technique (CAP assay) is described. With this method, we observed thein vitro anticancer efficiency of several antineoplastics on human solid tumors and acute non-lymphatic leukemia (ANLL) specimen. Comparing with the conventional two-layer agar culture assay (2-LAC assay). The CAP-assay had a higher culture success rate, higher plating efficiency (PE) and shorter experimental period. The preliminary data suggesting and that the CAP assay has the potential to replace the conventional 2- LAC assay for invitro drug- sensitivity testing and may be applied clinically.

Key words

glass capillary cell culture drug- sensitivity test 


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Copyright information

© Chinese Journal of Cancer Research 1992

Authors and Affiliations

  • He Zhimin 
    • 1
  • Wei Liyong 
    • 1
  • Peng Xiange 
    • 1
  1. 1.Research Lab. of PharmacologyHunan Medical UniversityChangsha

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