Indian Journal of Otolaryngology

, Volume 41, Issue 3, pp 108–110 | Cite as

Comparative study of Astemizole—A new H1 antagonist with a conventional antihistaminic in patients with allergic rhinitis

  • Thomas Sen Bhanu
  • Mathew Thariyan
  • Molly Thomas


A double blind study to evaluate in allergic rhinitis the efficacy of Astemizole with a classical antihistaminic—Chlorpheneramine is described. The results indicate that there is a significantly better clinical improvement with Astemizole compared with Chlorpheneramine. Except of weight gain, adverse Cholinergic and sedative effects were also minimal with Astemizole.


Allergic Rhinitis Terfenadine Astemizole Chlorpheniramine Anticholinergic Side Effect 
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Copyright information

© Association of Otolaryngologists of India 1989

Authors and Affiliations

  • Thomas Sen Bhanu
    • 1
  • Mathew Thariyan
    • 1
  • Molly Thomas
    • 2
  1. 1.the Department of Otorhinolaryngology, Speech & HearingChristian Medical College & HospitalVelloreS. India
  2. 2.the Department of Clinical PharmacologyChristian Medical College & HospitalVelloreS. India

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