Abstract
A double blind study to evaluate in allergic rhinitis the efficacy of Astemizole with a classical antihistaminic—Chlorpheneramine is described. The results indicate that there is a significantly better clinical improvement with Astemizole compared with Chlorpheneramine. Except of weight gain, adverse Cholinergic and sedative effects were also minimal with Astemizole.
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Bhanu, T.S., Thariyan, M. & Thomas, M. Comparative study of Astemizole—A new H1 antagonist with a conventional antihistaminic in patients with allergic rhinitis. Indian J Otolaryngol 41, 108–110 (1989). https://doi.org/10.1007/BF02994225
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DOI: https://doi.org/10.1007/BF02994225