Clinical Reviews in Allergy

, Volume 3, Issue 2, pp 249–267 | Cite as

Pulmonary manifestations of the rheumatic diseases

  • Dennis W. Boulware
  • David N. Weissman
  • N. James Doll


The collagen vascular diseases represent a heterogeneous group of multisystem disorders with a wide range of clinicopathologic features. Although these diseases represent distinct clinical entities, a great deal of overlap exists between them. For example, the diffuse interstitial fibrosis of SLE, RA, DMPM, PSS, and MCTD are indistinguishable clinically, radiographically, and histologically. Conversely, the pulmonary manifestations of the various vasculitides all differ significantly from each other in their clinicopathologic presentation, as well as in their response to therapy.

For diagnostic purposes, histologic evidence will usually be required for the pulmonary manifestations of the rheumatic diseases. Therapy must then be individualized for each of these entities, as the protocol and response are variable.


Systemic Lupus Erythematosus Ankylose Spondylitis Idiopathic Pulmonary Fibrosis Interstitial Lung Disease Mixed Connective Tissue Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Humana Press Inc. 1985

Authors and Affiliations

  • Dennis W. Boulware
    • 1
  • David N. Weissman
    • 1
  • N. James Doll
    • 1
  1. 1.Section of Clinical Immunology/Rheumatology, Department of MedicineTulane University School of MedicineNew Orleans

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