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Instrumental neutron activation analysis of kidney stones


Kidney stone samples of the types calcium oxalate, uric acid, and xanthine were analyzed for their elemental contents by neutron activation analysis to study both the elemental correlation and influence of element on stone precipitation processes. Elements, such as Al, Au, Br, Ca, Cl, Co, Cr, Fe, Hg, I, K, Mg, Na, Sb, Se, Sr, and Zn, were determined quantitatively. Calcium oxalate stones contained higher concentration of all the elements analyzed compared to uric acid or xanthine stones. The concentrations of Cl, Fe, K, Na, Sr, and Zn were relatively higher than Au, Co, Cr, and Sb. A positive correlation exists between Ca and Zn, whereas a negative correlation exists between Sr and Ca. Zinc may play an important role in the formation of calcium oxalate stone.

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  1. R. M. Kark and J. H. Oyama,Modern Nutrition in Health and Disease, R. S. Goodhart and M. E. Shills, eds. Lea and Febiger, Philadelphia, 1980, pp. 1035–1038.

    Google Scholar 

  2. R. J. Reveillaud, M. Daudon, M. F. Protat, and G. Ayrole,Eur. Urol. J. 6, 161 (1980).

    CAS  Google Scholar 

  3. T. Lewas, A. D. Callar, and J. Feria,J. Radioanal. Chem. 13, 75 (1973).

    Article  Google Scholar 

  4. I. Donev, S. Mashkarov, L. Maritchkova, and G. GostevJ. Radioanal. Chem. 37, 441 (1977).

    Article  CAS  Google Scholar 

  5. L. J. Jacimovic, R. Draskovic, and B. Ostojic,J. Radioanal. Chem. 37, 415 (1977).

    Article  CAS  Google Scholar 

  6. S. M. Lin, C. H. Chiang, C. H. Huang, and C. L. Tseng,Radioanal. Nucl. Chem. Lett. 96, 153 (1985).

    Article  CAS  Google Scholar 

  7. S. M. Lin, C. L. Tseng, and M. H. Yang,Appl. Radiat. Isol. 38, 635 (1987).

    Article  CAS  Google Scholar 

  8. A. A. Levison, M. Nosal, M. Davidman, E. L. Prien, and R. G. Stevenson,Invest. Urol. 15, 270 (1978).

    Google Scholar 

  9. I. Durak, A. Yasar, Z. Yurtarslani,B. J. Urol. 62, 203 (1988).

    Article  CAS  Google Scholar 

  10. E. Z. Hazarika and B. Rao,Indian. J. Med. Res. 62, 776 (1974).

    PubMed  CAS  Google Scholar 

  11. A. Hesse, H. J. Dietze, W. Berg, and E. Hienzsch,Eur. Urol. J. 3, 359 (1977).

    CAS  Google Scholar 

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Sarmani, S., Kuan, L.L. & Bakar, M.A.A. Instrumental neutron activation analysis of kidney stones. Biol Trace Elem Res 26, 497–502 (1990).

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Index Entries

  • Neutron activation analysis
  • trace elements
  • kidney stones
  • urinary calculi