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Journal of Solid-Phase Biochemistry

, Volume 4, Issue 1, pp 43–55 | Cite as

Regeneration of atp by immobilized microbial cells and its utilization for the synthesis of ATP and CDP-Choline

  • Yutaka Ado
  • Yukie Suzuki
  • Toshio Tadokoro
  • Kazuo Kimura
  • Hirotoshi Samejima
Article
  • 42 Downloads

Abstract

A number of fermentative methods for the production of various important nucleotides from their precursors have been developed in Japan, and some of these nucleotides have been industrially produced for more than a decade. For the production of these nucleotides, required ATP is usually supplied to the fermentation media either exogenously or by the naturally occurring ATP regenerating system involved in microbial cells. In this paper, the authors describe an attempt to immobilize ATP-regenerating microbial cells and then utilize such immobilized cells for the continuous production of various nucleotides.

Keywords

Chitosan Microbial Cell Immobilize Cell Ethylcellulose Native Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Humana Press Inc. 1979

Authors and Affiliations

  • Yutaka Ado
    • 1
  • Yukie Suzuki
    • 1
  • Toshio Tadokoro
    • 1
  • Kazuo Kimura
    • 1
  • Hirotoshi Samejima
    • 1
  1. 1.Tokyo Research LaboratoryKyowa Hakko Kogyo Co., Ltd.Machida-shi, TokyoJapan

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