A biased solid-phase radioimmunoassay for thyroxine (T4) using T4-125I presaturated antibodies

  • Howard H. Weetall
  • Gerald Odstrchel


An assay for thyroxine (T4) is demonstrated using specific antibodies covalently coupled to controlled pore glass (CPG). In this assay immobilized antibodies saturated with labeled T4 are employed in a preloaded unit tube configuration. These complexes are stable for long periods of time when stored in buffer. This concept results in a highly reproducible and sensitive assay for T4 that requires a single pipetting step.


Thyroxine Aryl Amine Merthiolate Control Pore Glass Label Antigen 
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Copyright information

© Humana Press Inc. 1977

Authors and Affiliations

  • Howard H. Weetall
    • 1
  • Gerald Odstrchel
    • 1
  1. 1.Corning Glass WorksCorning, New York

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