Biological discrimination between calcium and strontium in kidneys and bone of young and adult rats

  • Etsuko Kobayashi
  • Naoko Sugihira
  • Kazuo T. Suzuki


Effects of aging on the biological discrimination between calcium (Ca) and strontium (Sr) by the kidneys and bone were studied in male and female rats of 5 to 50 wk of age by examining Sr/Ca ratios in the plasma, urine, and bone. The Ca−Sr discrimination at the reabsorption process in the kidneys was not affected by aging in male or female rats. On the other hand, discrimination between the two elements was shown to be age-related at the absorption process in the digestive tract, and became more strict with age. The reverse situation was observed in the discrimination of Ca and Sr in the femur; younger rats discriminated the two elements more strictly than older animals.

Index Entries

Strontium-calcium discrimination aging strontium/calcium ratio bone reabsorption rat 


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Copyright information

© Humana Press Inc. 1991

Authors and Affiliations

  • Etsuko Kobayashi
    • 1
  • Naoko Sugihira
    • 1
  • Kazuo T. Suzuki
    • 1
  1. 1.National Institute for Environmental StudiesTsukuba, IbarakiJapan

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