Medical Oncology

, Volume 11, Issue 1, pp 1–6 | Cite as

Growth factors and hematopoietic recovery

  • Subhash C. Gulati
  • Ravi Gopal
  • Judith B. Prowda
  • Stanislov Spanik
  • Maneesh Jain
  • Ajay Gopal
Review Article


Availability of hematopoietic growth factors (GC-SF, GM-CSF, erythropoietin,etc.) has started a new arena of dose-intensification. The use of such growth factors has resulted in faster hematopoietic recovery of cancer patients and now offers several new treatment modifications. These include: (1)dose-intensification without hematopoietic stem cell support, (2) speedier hematopoetic recovery after hematoablative therapy and stem cell transplantation (allogeneic or autologous); (3) use of combination of growth factors, and (4) improvement in the delivery of anti-microbial drugs which are toxic towards hematopoietic cells (Gancyclovir, Bactrim,etc.). The above treatment strategies are under active clinical trials and can provide improved, cost-effective methods of treating patients with cancer.

Key Words

Growth factors hematopoietic recovery 


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Copyright information

© Humana Press Inc. 1994

Authors and Affiliations

  • Subhash C. Gulati
    • 1
  • Ravi Gopal
    • 1
  • Judith B. Prowda
    • 1
  • Stanislov Spanik
    • 1
  • Maneesh Jain
    • 1
  • Ajay Gopal
    • 1
  1. 1.Division of Hematology OncologyCornell University Medical CollegeNew York

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