Journal of Genetics

, Volume 51, Issue 1, pp 1–6 | Cite as

A mosaic mouse with an anomalous segregation ratio

  • T. C. Carter


A mouse, heterozygous for the semi-dominant colour and anaemia mutantW v, showed two patches of full pigmentation (i.e. lackingW v); she bred as though her ovaries were partly deficient of the type allele +w. Point mutation and deletion fail to provide satisfactory explanations; non-disjunction provides a possible explanation; somatic reduction and somatic crossing-over, not previously considered as possible mechanisms of mammalian mosaic formation, would fit the facts well. They could also account for some other mosaic mammals which were hitherto difficult to explain. It is established thatW v, like other mutants, is autonomous in its action on pigmentation.


Daughter Cell Recessive Phenotype Germinal Tissue Twin Spot Recessive Marker 
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Copyright information

© Indian Academy of Sciences 1953

Authors and Affiliations

  • T. C. Carter
    • 1
  1. 1.Medical Research Council Scientific StaffInstitute of Animal GeneticsEdinburgh

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