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Journal of Genetics

, 54:42 | Cite as

Vacillans, a neurological mutant in the house mouse linked with brown

With one text-figure
  • J. L. Sirlin
Article

Summary

Vacillans is a gene that conditions a complex syndrome involving the muscular co-ordination, behaviour and reflexes, as well as some metabolic abnormality. The syndrome seems to a large extent independent of the residual genotype. It behaves as a recessive, and the symbolvc is proposed. Vacillans is linked withbrown, in the linkage group VIII, with a recombination value of 5.5 ±1.9% in females. Double heterozygotes of vacillans andshaker-1,agitans, ataxia andreeler show no interaction. The compoundvc/vc;sh-1/sh-1 is described.

Keywords

House Mouse Recombination Fraction Double Heterozygote Adult normM Mouse Bridge Test 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Carter, T. C. &Falconer, D. S. (1951). Stocks for detecting linkage in the mouse, and the theory of their design.J. Genet. 50, 307–23.CrossRefGoogle Scholar
  2. Ealconer, D. S. (1951). Two new mutants, ‘trembler’ and ‘reeler’, with neurological actions in the house mouse (Mus musculus L.).J. Genet. 50, 192–201.Google Scholar
  3. Grüneberg, H. (1952).The Genetics of the Mouse, 2nd ed., pp. xiv + 650. The Hague: Martinus Nijhoff.Google Scholar
  4. Hoecker, G., Martinez, A., Markovic, S. &Pizarro, O. (1954). Agitans, a new mutation in the house mouse (with neurological effects).J. Hered. 45, 10–14.Google Scholar
  5. Li, C. C. (1948).An Introduction to Population Genetics, pp. 321. Peiping: National Peking University Press.Google Scholar
  6. Lyon, M. F. (1951). Hereditary absence of otoliths in the house mouse.J. Physiol. 114, 410–18.PubMedGoogle Scholar
  7. Lyon, M. F. (1955). Ataxia: a new recessive mutant in the house mouse.J. Hered. 46, 77–80.Google Scholar
  8. Mouse News Letter (1953),8, 18–19.Google Scholar
  9. Russell, E. S. (1946). A quantitative histological study of the pigment found in the coat-color mutants of the house mouse. I. Variable attributes of the pigment granules.Genetics,31, 327–46.PubMedGoogle Scholar

Copyright information

© Indian Academy of Sciences 1956

Authors and Affiliations

  • J. L. Sirlin
    • 1
    • 2
  1. 1.Institute of Biology ‘Juan Noé’University of ChileChile
  2. 2.Institute of Animal GeneticsUniversity of EdinburghEdinburgh

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