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Archives of Pharmacal Research

, Volume 22, Issue 4, pp 435–436 | Cite as

Total synthesis of (±)-homoepibatidine

  • Yong-Hyun Kim
  • Do-Youn Won
  • Chang-Young Oh
  • Kee-Young Lee
  • Jin-Hyun Jeong
  • Young-Hoon Jung
  • Won-Hun Ham
Rapid Communication

Abstract

Total synthesis of (±)-homoepibatidine (2), which contains the 8-azabicyclo[3.2.1] octane ring system, was achieved by using palladium-catalyzed Heck-type coupling reaction from3.

Key words

Alkaloids Analgesics Palladium Stereocontrol 

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Copyright information

© The Pharmaceutical Society of Korea 1999

Authors and Affiliations

  • Yong-Hyun Kim
    • 1
  • Do-Youn Won
    • 1
  • Chang-Young Oh
    • 1
  • Kee-Young Lee
    • 1
  • Jin-Hyun Jeong
    • 2
  • Young-Hoon Jung
    • 1
  • Won-Hun Ham
    • 1
  1. 1.College of PharmacySungkyunKwan UniversitySuwonKorea
  2. 2.College of PharmacyKyung Hee UniversitySeoulKorea

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