Archives of Pharmacal Research

, Volume 28, Issue 11, pp 1236–1238 | Cite as

Ophiopojaponin D, a new phenylpropanoid glycoside fromOphiopogon Japonicus Ker-Gawl

  • Hao Fu Dai
  • Wen Li Mei


A new phenolic glycoside, ophiopojaponin D (1), together with two known compounds, was isolated from the tubers of a famous traditional Chinese herb-Ophiopogon japonicus Ker-Gawl. The spectroscopic and chemical data revealed their structures to be β-tetradecyloxy-4-hydroxy-allylbenzene-4-O-α-L-rhamnopyranosyl (1→6)-ß-D-glucopyranoside (1), 3, 4-dihy-droxy-allylbenzene-4-O-α-L-rhamnopyranosyl (1→6)-ß-D-glucopyranoside (2) and L-pyro-glutamic acid (3).

Key words

Ophiopogon japonicus Phenolic glycoside Ophiopojaponin D 


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  1. Adinolfi, M., Parrilli, M., and Zhu, Y. X., Terpenoid glycosides fromOphiopogon japonicus root.Phytochemistry, 29, 1696–1699 (1990).CrossRefGoogle Scholar
  2. Branke, J. T. and Hashilinger, E., Spirostanol glycoside from the tuber ofOphiopogon japonicus.Liebigs Ann, 587–589 (1995).Google Scholar
  3. Chen, J. J., Zhu, Z. L., and Luo, S. D., Cixi-ophiopogon A and B1, C127 Steroidal glycosides fromOphiopogon japonicum.Acta Botanica Yunnanica, 22, 97–102 (2000).Google Scholar
  4. Dai, H. F., Zhou, J., Ding, Z. T., and Tan, N. H., Two new steroidal glycosides fromOphiopogon japonicus.Chin. Chem. Lett., 11, 901–904 (2000).Google Scholar
  5. Hao, X. Y., Tan, N. H., and Zhou, J., Constituents ofGastrodia elata in Guizhou.Acta Botanica Yunnanica, 22, 81–84 (2000).Google Scholar
  6. Jiangsu New Medical College,The Dictionary of Traditional Chinese Medicines, Shanghai People’s Press, Shanghai, P. 1024 (1977).Google Scholar
  7. Nakanishi, H. and Kameda, N., Studies on the component ofOphiopogonis tuber (China) II.Chem. Pharm. Bull., 107, 780–784 (1987).Google Scholar
  8. Nohara, T., Miyahara, K., and Kawasaki, K. I., Steroid saponins and sapogenins of underground parts ofTrillium kamtschatium Pall. II. Pennogenin- and kryptogenin 3-O- glycosides and related compounds.Chem. Pharm. Bull., 23, 872–885 (1975).Google Scholar
  9. Tada, A., Kasai, R., and Saitoh, T., Studies on the constituents ofOphiopogonis tuber. V. Isolation of novel class of homoisoflavonoids and determination of their structures (1).Chem. Pharm. Bull., 28, 1477–1484 (1980).Google Scholar
  10. Tada, A., Kasai, R., and Saitoh, T., Studies on the constituents ofOphiopogonis tuber. VI. Structures of homoisoflavonoids (2).Chem. Pharm. Bull., 28, 2039–2044 (1980).Google Scholar
  11. Tada, A., Kobayashi, M., and Shoji, J., Studies on the constituents ofOphiopogonis tuber. III. On the structures of ophiopogonin D.Chem. Pharm. Bull., 21, 308–311 (1973).Google Scholar
  12. Tada, A. and Shoji, J., Studies on the constituents ofOphiopogonis tuber. II. On the structures of ophiopogon B.Chem. Pharm. Bull., 20, 1729–1734 (1972).Google Scholar
  13. Zhou, Z. H., Wang, J. L., and Yang, R., Three glycosides from the Chinese Dragon’s Blood (Dracaena cochinchinensis).Chinese Traditional and Herbal Drugs, 30, 801–804 (1999).Google Scholar

Copyright information

© The Pharmaceutical Society of Korea 2005

Authors and Affiliations

  1. 1.State Key Laboratory of Tropical Crops Biotechnology, the Institute of Tropical Bioscience and BiotechnologyChinese Academy of Tropical Agriculture SciencesHaikouChina

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