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Synthesis and antimicrobial activity of new substituted anilinobenzimidazoles

  • Z. M. Nofal
  • H. H. Fahmy
  • H. S. Mohamed
Research Articles Articles

Abstract

A series of benzimidazole derivatives carrying different heterocycles such as 1,2,3-thiadiazole, 1,3,4-thiadiazole, thiazolidine, 2,3-dihydro-thiazole, 1,3,4-oxadiazole, semicarbazone and substituted thiosemi-carbazones were synthesized. Also a series of 1-methylbenzimidazole carrying hydroxy ethyl-amide, substituted sulfonyl hydrazide and benzoyl hydrazide from aminobenzoyl group at position 2 of 1-methylbenzimidazole were synthesized. The antimicrobial evaluation of some of the new compounds was carried out.

Key words

1,2,3-Thiadiazol Oxadiazol Semicarbazone Substituted thiosemicarbazones Sulfonyl hydrazide Benzoyl hydrazide 

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Copyright information

© The Pharmaceutical Society of Korea 2002

Authors and Affiliations

  1. 1.Therapeutical Chemistry Dept.National Research CentreDokki, CairoEgypt

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