Archives of Pharmacal Research

, Volume 20, Issue 6, pp 610–619 | Cite as

Synthesis of 1-(heterocyclic substituted anilino)-9H-thioxanthon-9-ones and their antitumor activity

  • Mahmoud T. Omar
Research Articles


Some new 9H-thioxanthen-9-one incorporated into heterocyclic systems such as pyridone8, pyrazoline9, pyranone11, iminopyrane12, furopyrimidine17, imidazothiazole19, thiazole21, triazine24 and other related compounds through a para imminophenyl grouping at position-1 of the thioxanthenone ring were synthesized and tested as antitumor agents, against L 1210 leukemia in mice. Some of the new compounds showed considerable antitumor activity.

Key words

Pyranone Furopyrimidine Imidazothiazole Triazine Antitumor activity 


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Copyright information

© The Pharmaceutical Society of Korea 1997

Authors and Affiliations

  • Mahmoud T. Omar
    • 1
  1. 1.Chemotherapeutic DepartmentNational Research CentreCairoEgypt

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