Antioxidative effects ofCichorium intybus root extract on LDL (Low Density Lipoprotein) oxidation
- 87 Downloads
The water extract ofCichorium intybus (WECI) showed a remarkable antioxidative effect on LDL, and inhibitory effects on the production of thiobarbituric acid reactive substance and the Degradation of fatty acids in LDL. Vitamin E and unsaturated fatty acids in LDL were protected by adding WECI from the effects of metal catalyzed LDL oxidation. From the results obtained, we conclude that LDL oxidation is inhibitedin vitro by the addition of WECI, and that LDL is protected by WECI from oxidative attack, as shown by agarose gel electrophoresis.
Key wordsAntioxidative activity Cichorium intybus (Compositae) LDL oxidation
Unable to display preview. Download preview PDF.
- Choi, J. H., Son, H. S., Kim, S. H., and Kim, T. W., Fatty acid composition and functional properties of LDL and oxidized LDL from human plasma.Journal of Korean Society Food Nutrition, 23, 402–408 (1994).Google Scholar
- Fogelman, A. M., Warden, C., Harberland, M. E., and Edwards, P. A., Macrophage lipoprotein receptors.Journal of Cell Science Supplment 9, 135–143 (1988).Google Scholar
- Ki, C. G., Yim, D. S., and Lee, S. Y., Biological activities of the root ofCichorium intybus.Natural Product Sciences, 5(4) 155–158 (1999).Google Scholar
- Lim, W. G., Resources Botany, Press of Seo II Co. p. 151 (1996).Google Scholar
- Reddy, B. S., Possible mechanism by which pro-and prebiotics influence colon carcinogenesis and tumor growth.Journal of Nutrition, 129, 1478–1482 (1999).Google Scholar
- Yang, C. Y., Gu, Z. W., Kim, T. W., Cotto, A. M., and Chan, L., Structure of apo B-100 of human LDL.Arteriosclerosis, 96–101 (1989).Google Scholar
- Yang, K. S. and Shim, J. M., Effect of Arctii Fructus on Low Density Lipoprotein Oxidation.Kor. J. Pharmacogn. 28(4) 275–279 (1997).Google Scholar