Archives of Pharmacal Research

, Volume 24, Issue 5, pp 431–436 | Cite as

Antioxidative effects ofCichorium intybus root extract on LDL (Low Density Lipoprotein) oxidation

  • Tae-Woong Kim
  • Ki-Sook Yang
Research Article Medicinal Chemistry & Natural Products


The water extract ofCichorium intybus (WECI) showed a remarkable antioxidative effect on LDL, and inhibitory effects on the production of thiobarbituric acid reactive substance and the Degradation of fatty acids in LDL. Vitamin E and unsaturated fatty acids in LDL were protected by adding WECI from the effects of metal catalyzed LDL oxidation. From the results obtained, we conclude that LDL oxidation is inhibitedin vitro by the addition of WECI, and that LDL is protected by WECI from oxidative attack, as shown by agarose gel electrophoresis.

Key words

Antioxidative activity Cichorium intybus (Compositae) LDL oxidation 


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Copyright information

© The Pharmaceutical Society of Korea 2001

Authors and Affiliations

  1. 1.Department of BiochemistryKangweon National UniversityChuncheonKorea
  2. 2.College of PharmacySookmyung Women’s UniversitySeoulKorea

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