Archives of Pharmacal Research

, Volume 24, Issue 4, pp 263–269 | Cite as

Facile synthesis and biological evaluation of heterocyclic compounds containing Diazepam

Research Article Medicinal Chemistry & Natural Products


Diazepamoxadiazoles4,5,6,12,14 and22 were prepared with the binary form system. Diazepamthiadiazoles15,20 and Diazepamtriazoles7,8,9,17,18,19 and21 were also shapely synthesized. Some of these compounds were screened to test their antibacterial activity againstE. coli andB. subtilis compounds 15 and 20 show potent activity against these bacteria.

Key words

Diazepam Biodynamic heterocyclic systems Triazoles Thiadiazoles Oxadiazoles 


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Copyright information

© The Pharmaceutical Society of Korea 2001

Authors and Affiliations

  1. 1.Department of Chemistry, Faculty of ScienceMansoura UniversityMansouraEgypt

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