Chinese Journal of Cancer Research

, Volume 9, Issue 2, pp 79–82 | Cite as

Influence of alpha-fetoprotein on the growth of tumor cellsin vitro

  • Wang Xingwang 
  • Xu Bin 
Basic Investigations


It has been recognized that alpha-fetoprotein (AFP), as an oncofetal antigen, re-expresses in large amounts in adult tumor cells and serves clinically useful purposes as a tumor marker assay. However, its biological activities are still far from clear. In the present study, the ability of AFP to stimulate tumor cell growth was observed byin vitro test system. The new finding indicates that AFP contributes to the generation and development of tumor and is an important target action site of tumor therapy.

Key words

Alpha-fetoprotein Liver neoplasma Animal model In vitro experiment 


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Copyright information

© Chinese Journal of Cancer Research 1997

Authors and Affiliations

  • Wang Xingwang 
    • 1
  • Xu Bin 
    • 1
  1. 1.Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai

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