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Acta Endoscopica

, Volume 21, Issue 2, pp 255–260 | Cite as

Mycobacterium paratuberculosis isole chez des patients atteints de maladie de Crohn Résultats préliminaires

  • J. Haagsma
  • Ch. J. J. Mulder
  • A. Eger
  • G. N. J. Tytgat
Article

Résumé

En 1913, Dalziél a décrit des observations compatibles avec une maladie de Crohn vraisemblablement en rapport avec une paratuberculose.

En 1984, Chiodini a isolé un Mycobacterium paratuberculosis chez des patients atteints de maladie de Crohn. Entre 1985 et 1990, nous avons isolé ’ trois souches de Mycobacterium paratuberculosis.

Depuis 1986, 4 autres groupes ont confirmé les résultats initiaux de Chiodini. Une étiologie microbienne de la maladie de Crohn, spécialement en rapport avec une mycobacterie type M. paratuberculosis, semble fondée sur des arguments de plus en plus prometteurs.

Mots-clés

bactériologie étiologie maladie de Crohn mycobactérie mycobacterium paratuberculose 

Mycobacterium paratuberculosis isolated from patients with Crohn ’s disease

Summary

En 1913, Dalziel described cases of probably Crohn ’ s disease, which could be related to paratuberculosis. In 1984 Chiodini isolated Mptbc from Crohn ’ a patients. We isolated between 1985-1990 3 strains of Mptbc. Since 1986 4 other groups confirmed the original results of Chiodini. Considering all possibilities a microbial aetiology, especially a mycobacterial one connected with Mptbc, seems more and more promising.

Key-words

aetiology bacteriology Crohn’s disease mycobacteria mycobacterium paratuberculosis 

Mycobacterium paratuberculosis aislado en pacientes con Enfermedad de Crohn. Resultados preliminares

Resumen

En 1913, Dalziel describió observaciones compatibles con una probable Enfermedad de Crohn relacionada con una paratuberculosis. En 1984, Chiodini aisló un Mycobacterium paratuberculosis en pacientes con Enfermedad de Crohn. Entre 1985 y 1990 hemos aislado trescepas de Mycobacterium tuberculosis.

Después de 1986, otros 4 grupos han confirmado los resultados iniciales de Chiodini. Una etiología microbiana de la Enfermedad de Crohn, especialmente relacionada con una micobacteria tipo M. paratuberculosis parece sostenida sobre bases más y más promisorias.

Palabras claves

bacteriología etiología Enfermedad de Crohn mycobacteria mycobacterium paratuberculosis 

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Références

  1. 1.
    DALZIEL T.K. — Chronic interstitial enteritis.BMJ, 1913, 2, 1068–1070.Google Scholar
  2. 2.
    VAN PATTER W. . — Pathology and Pathogenesis of regional enteritis, Ph-D-thesis, University of Minnesota, 1952.Google Scholar
  3. 3.
    CHIODINI R.J., VAN KRUININGEN H.J., MERKAL R.S., THAYER W.R., CONTU J.A. — Characteristics of an unclassified Mycobacterium species isolated from patients with Crohn ’s disease.J. Clin. Microbiol., 1984 ; 20, 966- 971.PubMedGoogle Scholar
  4. 4.
    JORGENSEN J.B. — An improved medium for culture of Mptbc from bovine faeces.Acta Vet. Scand., 1982, 23, 325–329.PubMedGoogle Scholar
  5. 5.
    MC FADDE, J.J, HERMAN TAYLOR J.J. — Personal communications 1987, 1989 and 1990.Google Scholar
  6. 6.
    CHIODINI R.J. — Crohn’ s Disease and the Mycobacterioses: a review and comparison of 2 disease entities.Clin. Microbiol. Rev., 1989, 2, 90–117.PubMedGoogle Scholar
  7. 7.
    COLOE P, WILKS C.R, LIGHTFOOT D., TOSOLINI F.A. — Isolation of Mptbc in Crohn’s disease.Austral. Microbiol, 1986, 7, 188A.Google Scholar
  8. 8.
    GITNICK G., COLLINS J., BEAMAN B., BROOKS D., ARTHRU M., IMAEDA T., PALIESCHESKY M. — Preliminary report on isolation of Mycobacteria from patients with Crohn’s disease.Dig. Dis. Sci., 1989, 34, 925–935.PubMedCrossRefGoogle Scholar
  9. 9.
    THOREL M.F. — Veterinary Institute Lyon. Personal communication 1989.Google Scholar
  10. 10.
    GRAHAM D. — Oral Presentation 31-08-1990. World Congress of Gastroenterology Sydney.Google Scholar
  11. 11.
    KREUZPAINTNER G., WALLNER A., KÖLBLE R. et al. — Spielen langsam wachsende Mykobacterien der Runyon gruppe III ätiologische eine Rolle bei M. Crohn. Zeitschrift fur Gastroenterologie 1989, 9, 494 A.Google Scholar
  12. 12.
    KOBAYASHI K., BLASER M.J., BROWN W.R. — Immunohistochemical examination for mycobacteria in intestinal tissue from patients with Crohn’s Disease.Gastroenterology, 1989, 96, 1009–1015.PubMedGoogle Scholar
  13. 13.
    DAS P.K., BLAAUWGEERS J.L.S., SLOB A.W., SPIES J., CHAND A., KOLK A.H. — On the mycobacterial aetiology of Crohn’s Disease.Gastroenterol., 1988, 94, A88.Google Scholar
  14. 14.
    MOKRESH A.H., BUTTER D.G. — Granulomatous Enteritis Following Oral Inoculation of Newborn Rabbits with Mycobacterial Paratuberculosis of Bovine Origin.Can. J. Vet. Res., 1990, 54, 313–319.PubMedGoogle Scholar
  15. 15.
    TYTGAT G.N.J., MULDER C.J.J. — The aetiology of Crohn’s Disease.Int. J. Colored Dig., 1986, 1, 188–192.CrossRefGoogle Scholar
  16. 16.
    BLAAUWGEERS H.L.L., MULDER C.J.J., DAS P.K., HAAGSMA J., TYTGAT G.N.J. — Crohn’s disease, a mycobacterial aetiology?Eur. J. Gastroenterol. Hepatol., 1990, 2, 237–240.Google Scholar

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • J. Haagsma
    • 1
  • Ch. J. J. Mulder
    • 2
  • A. Eger
    • 1
  • G. N. J. Tytgat
    • 3
  1. 1.Central Veterinary Institute, EdelhertwegLelystad
  2. 2.Rijnstate Hospital ArnhemNetherland
  3. 3.AMC Amsterdam

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