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Breast Cancer

, Volume 11, Issue 2, pp 210–213 | Cite as

A Case of Breast Cholesterol Granuloma Accompanied by Cancer

  • Chizu Furuhira
  • Akira Ohshima
  • Kazuo Shimada
  • Syoji Kuroki
  • Kenji Nakano
  • Mikimasa Ishikawa
  • Hidetaka Yamamoto
  • Masao Tanaka
Case Report

Abstract

Cholesterol granuloma of the breast is a very rare benign disease with clinical and imaging features that are often indistinguishable from cancer preoperatively. We report a case of breast cholesterol granuloma accompanied by cancer. The patient was a 78-year-old woman who complained of a lump in her right breast. Mammography and ultrasonography showed a well-circumscribed mass. Fine needle aspiration cytology showed many cholesterol crystals and inflammatory cells without malignancy. With a diagnosis of cholesterol granuloma, tumor extirpation was performed. Histopathologic examination revealed cholesterol granuloma together with breast cancer, and additional partial mastectomy was subsequently performed. It is noted that breast cholesterol granuloma could be accompanied by cancer.

Key words

Cholesterol granuloma Breast cancer 

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References

  1. 1).
    Ishizaki M, Ohsumi S, Takashima S, Mandai K: Two cases of cholesterol granuloma of the breast.Breast Cancer 8:158–161, 2001.PubMedCrossRefGoogle Scholar
  2. 2).
    Smith GL, Hicks P, Wijesinghe DP, Holme TC: Cholesterol granuloma of the breast presenting an intracystic papilloma.Brit J Radiol 70:1178–1179,1997.PubMedGoogle Scholar
  3. 3).
    Wilhelmus JL, Schrodt GR, Mahaffey LM: Cholesterol granulomas of the breast: A lesion which clinically mimics carcinoma.Am J Clin Pathol 77:592–597, 1982.PubMedGoogle Scholar
  4. 4).
    Reynolds HE, Cramer HM: Cholesterol granuloma of the breast: A mimic of carcinoma.Radiology 191:249–250,1994.PubMedGoogle Scholar
  5. 5).
    Tsuji H, Satoh Y, Ohtsuka K, Ono K, Kawakami S, Furutani S, Umemori Y, Ishizaki M, Kunitomo T: A case of cholesterol granuloma of the breast.Gekashinryou 7:1107–1110,1989.Google Scholar
  6. 6).
    Al-Amer AF, Walia HS, Madda JP: Cholesterol granuloma of the peritoneum.Can J Surg 33:410–413,1990.PubMedGoogle Scholar
  7. 7).
    Nast CC, Cohen AH: Renal cholesterol granulomas, identification and morphological pattern of development.Histopathology 9:1195–1204,1985.PubMedCrossRefGoogle Scholar
  8. 8).
    Lin JI, Tseng CH, Marsidi PJ, Bais VC: Cholesterol granuloma of right testis.Urology 14:522–523,1979.PubMedCrossRefGoogle Scholar
  9. 9).
    Rubinstein A, Brenner S: Idiopathic lipogranulomatosis of spleen and periaortic lymph nodes with non-caseating granulomas of the liver.Hum Pathol 13:1133–1135,1982.PubMedCrossRefGoogle Scholar
  10. 10).
    Bundgaard N, Eriksen HE, Greisen O: Inflamed ade-nolymphoma with cholesterol granuloma.J Laryngol Otol 101:967–970,1987.PubMedCrossRefGoogle Scholar
  11. 11).
    Dixon JM: Periductal mastitis/duct ectasia.World J Surg 13:715–720,1989.PubMedCrossRefGoogle Scholar
  12. 12).
    Döring L, Wedemeier G: Cholesteringranulom der weiblichen Brust.Chirung 45:502–521,1974.Google Scholar
  13. 13).
    Page DL, Anderson TJ: Miscellaneous non-neoplastic conditions. In: Diagnostic histopathology of the breast, Churchill Livingstone, New York, pp62–64, 1987.Google Scholar

Copyright information

© The Japanese Breast Cancer Society 2004

Authors and Affiliations

  • Chizu Furuhira
    • 1
  • Akira Ohshima
    • 1
  • Kazuo Shimada
    • 1
  • Syoji Kuroki
    • 1
  • Kenji Nakano
    • 1
  • Mikimasa Ishikawa
    • 1
  • Hidetaka Yamamoto
    • 2
  • Masao Tanaka
    • 1
  1. 1.Department of Surgery and OncologyGraduate School of Medical Sciences, Kyushu UniversityFukuokaJapan
  2. 2.Department of Anatomic PathologyGraduate School of Medical Sciences, Kyushu UniversityJapan

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