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Breast Cancer

, Volume 10, Issue 4, pp 356–360 | Cite as

Invasive micropapillary carcinoma of the breast with minimal regional lymph node metastasis regardless of the huge size: Report of a case

  • Takashi Akiyoshi
  • Takashi Nagaie
  • Masanori Tokunaga
  • Masaaki Tajima
  • Makoto Morita
  • Akio Nakatsuka
  • Satoshi Taga
  • Shigeki Wakiyama
  • Masahiko Ikebe
  • Kozo Nakanishi
  • Mitsunori Hashimoto
  • Taisuke Toyomasu
  • Kazuo Nakanishi
Case Report

Abstract

We present a 38-year-old premenopausal Japanese woman with invasive micropapillary carcinoma (IMC) of the left breast with minimal lymph node metastasis despite a huge size. The patient noticed a left breast mass and a bloody nipple discharge 2 years before admission. On admission, physical examination revealed a huge, elastic hard mass with skin ulcer 12 × 12 cm in diameter occupying the entire left breast. The patient underwent modified radical mastectomy with level III lymph node dissection, and the defect was reconstructed with a vertical rectus abdominis myocutaneous flap. Histopathologically, IMC comprised about 60% of the tumor, admixed with papillotubular and mucinous carcinoma. Only one of twenty-five lymph nodes had tumor metastasis. The patient remains well 8 months postoperatively without any signs of recurrence.

Key words

Invasive micropapillary carcinoma Lymph node 

Abbreviations

IMC

Invasive micropapillary carcinoma

ER

Estrogen receptor

PgR

Progesterone receptor

CPA

Cyclophosphamide

ADM

Adriamycin

5-FU

5-fluorouracil

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Copyright information

© The Japanese Breast Cancer Society 2003

Authors and Affiliations

  • Takashi Akiyoshi
    • 1
  • Takashi Nagaie
    • 1
  • Masanori Tokunaga
    • 1
  • Masaaki Tajima
    • 1
  • Makoto Morita
    • 1
  • Akio Nakatsuka
    • 1
  • Satoshi Taga
    • 1
  • Shigeki Wakiyama
    • 1
  • Masahiko Ikebe
    • 1
  • Kozo Nakanishi
    • 1
  • Mitsunori Hashimoto
    • 1
  • Taisuke Toyomasu
    • 1
  • Kazuo Nakanishi
    • 2
  1. 1.Department of SurgeryAso lizuka HospitalFukuokaJapan
  2. 2.Department of PathologyAso lizuka HospitalJapan

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