Abstract
Background
To diagnose intraductal lesions endoscopically the Japanese Association of Mammary Ductoscopy classified the endoscopical appearance of lesions into three types. We investigated the correlation between endoscopic classification and histological diagnosis.
Methods
From April 1998 to February 2001, we enrolled 129 female patients who were diagnosed histologically and whose intraductal lesions were detected by mammary ductoscopy. The endoscopic classification consists of three types. The polypoid type is a localized expansive lesion. This type is divided into two subtypes, the solitary subtype (solitary polypoid lesion) and the multiple subtype (multiple polypoid lesions). The combined type is polypoid lesion(s) coexisting with a superficial type. The superficial type is a superficial spreading lesion such as a continuous luminal irregularity accompanied by no obvious elevations.
Results
There were 65 cases of breast cancer and 64 cases of benign papillary lesions. Fifty-four cases of benign papillary lesions and 7 cases of breast cancer were classified as the polypoid-solitary type. Seven benign cases and 13 cases of cancer were classified as the polypoid-multiple type. Two benign cases and 16 cases of cancer were classified as the combined type. Only one benign case and 29 cases of cancer were classified as the superficial type. There is significant correlation between endoscopical types and the histological diagnosis (p < 0.0001).
Conclusions
Endoscopic classification is useful to diagnose intraductal lesions.
Similar content being viewed by others
References
Atkins H, Wolff B: Discharges from the nipple.Brit J Surg 51: 602–606, 1964.
Ohuchi N, Furuta A, Mori S: Management of ductal carcinoma in situ with nipple discharge: Intraductal spreading of carcinoma in unfavorable pathologic factor for breast conserving surgery.Cancer 74: 1294–1302, 1994.
Ikeda T, Akiyama F, Hiraoka M,et al: The current status of treatment of ductal carcinoma in situ of Japanese women, especially breast conserving operation in relation to the surgical margin and short term outcome.Breast Cancer 5: 53–58, 1998.
Fish EB, Chapman J-AW, Miller NA,et al: Assessment of treatment for patients with primary ductal carcinoma in situ in the breast.Ann Surg Oncol 5: 724–732, 1998.
Makita M, Sakamoto G, Akiyama F,et al: Duct endoscopy and endoscopic biopsy in the evaluation of nipple discharge.Breast Cancer Res Treat 18: 179–188, 1991.
Makita M, Namba K, Aoyama E,et al: Significances of duct endoscopy in diagnosis of nipple discharge.Jpn J Breast Cancer 10: 399–403, 1995 (in Japanese with English summary).
Namba K, Sakamoto G, Akiyama F,et al: Intraductal biopsy of the breast (I.D.B.B.) for intraductal lesions: a case of breast cancer diagnosed by I.D.B.B.Jpn J Breast Cancer 4: 253–258, 1989 (in Japanese with English summary).
Japanese Association of Mammary Ductoscopy: Endoscopic classification of intraductal lesions. Proceedings of 6th annual meeting of Japanese Association of Mammary Ductoscopy, 2001.
Makita M, Namba K, Aoyama E,et al: Endoscopic diagnosis of intraductal lesions in patients with nipple discharge.Jpn J Breast Cancer 11: 134–141, 1996 (in Japanese with English summary).
Makita M, Namba K, Aoyama E,et al: Correlation between duct endoscopic appearance of intraductal spread of carcinoma and clinical features in breast cancer with nipple discharge.Jpn J Breast Cancer 11: 303–309, 1996 (in Japanese with English summary).
Makita M, Akiyama F, Kimura K,et al: Mammary ductoscopic diagnosis of intraducal spread of breast cancer.Jpn J Breast Cancer 16: 274–278, 2001 (in Japanese with English summary).
Kraus FT, Neubecker RD: The differential diagnosis of papillary tumors of the breast.Cancer 15: 444–455, 1962.
Author information
Authors and Affiliations
Additional information
Reprint requests to Masujiro Makita, Department of Breast Surgery, Cancer Institute Hospital, 1-37-1, Kami-lkebukuro, Toshima-ku, Tokyo 170-8455, Japan.
About this article
Cite this article
Makita, M., Akiyama, F., Gomi, N. et al. Endoscopic classification of intraductal lesions and histological diagnosis. Breast Cancer 9, 220–225 (2002). https://doi.org/10.1007/BF02967593
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02967593