Breast Cancer

, Volume 7, Issue 2, pp 157–159 | Cite as

A case of breast cancer with endocrine features

  • Atsuo Tsuchiya
  • Yoshihiro Nozawa
  • Arifumi Hasegawa
  • Masahiro Kishimoto
  • Seiichi Takenoshita
Case Report


Cancer with endocrine features rarely occurs in the breast. We report a case of breast cancer with endocrine features in an 80-year-old woman. The tumors were treated by wide excision and a postoperative histopathologic diagnosis of carcinoma of the breast with endocrine features was made. Immunostaining was positive for chromogranin A, neuron-specific enolase and synaptophysin, but weakly argyrophilic. Widespread metastases occurred two months postoperatively, and the patient died of breast cancer 6 months after the first treatment.

Key words

Breast cancer Endocrine features Chromogranin 



Carbohydrate antigen 15-3


Carcinoembryonic antigen


Luteinizing hormone


Follicle stimulating hormone


Parathyroid hormone


Anti-epitherial keratin 1/3


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Copyright information

© The Japanese Breast Cancer Society 2000

Authors and Affiliations

  • Atsuo Tsuchiya
    • 1
  • Yoshihiro Nozawa
    • 2
  • Arifumi Hasegawa
    • 1
  • Masahiro Kishimoto
    • 1
  • Seiichi Takenoshita
    • 1
  1. 1.Department of Surgery IIFukushima Medical University School of MedicineJapan
  2. 2.Department of Pathology IFukushima Medical University School of MedicineJapan

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