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Breast Cancer

, 3:151 | Cite as

Recent progress in breast conserving therapy: From experiences in Japan

  • Hiroki Koyama
  • Hideo Inaji
  • Shinzaburo Noguchi
  • Kazuyoshi Motomura
Review Article

Abstract

Breast conserving therapy (BCT) was conducted in 22.1% of breast cancer patients in 1994 in Japan and is being performed with increasing frequency. According to the data already published, 10—27% of patients treated withBCT had a positive surgical margin. The recurrence rate in the breast is 1—2% annually. The 5-year overall survival in patients mostly consisting of stage I is 90% or higher at the present time. A case-control analysis of a multicenter study revealed that significant risk factors for breast recurrence were a positive surgical margin and absence of radiation therapy. Progress in basic research and diagnosis has also been instrumental in improving treatment results.

Key words

Breast conserving therapy Breast recurrence Radiation therapy Endocrine therapy 

Abbreviations

BCT

Breast conserving therapy

TND

Tumor nipple disrance

EIC

Extensive intraductal component

AgNor

Argyrophylic nucleolar organizer region

FDC

Forefront intraductal cancerous area

CIV

Central invasive area

ER

Estrogen receptor

RFLP

Restriction fragment length polymorphism

MRI

Magnetic resonance imaging

CT

Computed tomography

RR

Risk ratio

RT

Radiation therapy

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Copyright information

© The Japanese Breast Cancer Society 1996

Authors and Affiliations

  • Hiroki Koyama
    • 1
  • Hideo Inaji
    • 1
  • Shinzaburo Noguchi
    • 1
  • Kazuyoshi Motomura
    • 1
  1. 1.Department of SurgeryOsaka Medical Center for Cancer and Cardiovascular DiseasesOsakaJapan

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