The properties of beta adrenergic blocking agents

  • R. G. Shanks


Observations in animals now indicate that adrenergic beta receptor blocking agents may possess in addition intrinsic sympathomimetic activity and a local anaesthetic action. Unlike other beta receptor blocking agents I.C.I. 50172 selectively blocks only the receptors in the heart. The role of these different properties in the beneficial effect these drugs is not yet clearly understood. Further studies comparing the effects of drugs with different properties in angina and cardiac arrhythmias are required. Such studies must be carried out with equivalent beta receptor blocking doses of the drugs.


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Copyright information

© Springer 1969

Authors and Affiliations

  • R. G. Shanks
    • 1
  1. 1.Department of Therapeutics and PharmacologyThe Queen's UniversityBelfast

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