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The action of tolbutamide on rat diaphragm

  • J. J. Connon
Article

Summary

PHYSIOLOGICAL concentrations of tolbutamide increased glucose uptake by the rat hemidiaphragm. The increase was not affected by excess insulin neutralising serum and although decreased by 0.006/M cysteine was still significantly greater than the basal uptake. These results suggest that the action of tolbutamide on glucose uptake is independent of insulin.

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Copyright information

© Springer 1969

Authors and Affiliations

  • J. J. Connon
    • 1
  1. 1.The Department of MedicineThe Queen’s University of BelfastBelfastUK

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