Disseminated tuberculosis with associated haematological disorders
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Six patients with “disseminated tuberculosis” and haematological abnormalities are presented. The difficulties in diagnosis have been stressed with misleading findings such as normal chest radiograph, negative sputum cultures and previous history of successful B.C.G. vaccination.
The importance of awareness of the possibility of the condition in a patient with an apparently primary haematological abnormality especially pancytopenia with pyrexia has been mentioned. The relative values of lymph node, liver and bone marrow biopsies are discussed. It is considered that bone marrow needle trephine biopsy has considerable potential.
One patient successfully vaccinated with B.C.G. presented with pyrexia and eosinophilia. Diagnosis was obtained by liver biopsy and antituberculous therapy resulted in complete recovery.
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