Irish Journal of Medical Science

, Volume 157, Issue 1, pp 5–7 | Cite as

Trisomy 18: A nine year review

  • A. Bergin
  • S. P. McManus
  • T. A. Clarke
  • M. Moloney


A RETROSPECTIVE study confirmed the incidence of Edward’s Syndrome to be 1 in 3349-considerably higher than reported in most comparable studies. Median survival of the liveborn infants was four days, with a mean of 17 days, and a range of one hour to ten weeks. Fifty per cent of all liveborn babies with this potentially lethal genetic condition were delivered by caesarean section. The role that prenatal foetal assessment, including foetal karyotyping, might play in identifying such affected foetuses and determining their method of delivery is discussed. This is particularly important in view of the fact that a considerable proportion of the mothers of offspring with this condition are of advanced maternal age and high parity.


Caesarean Section Caesarean Section Rate Polyhydramnios Lower Segment Caesarean Section Affected Foetus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer 1988

Authors and Affiliations

  • A. Bergin
    • 1
  • S. P. McManus
    • 1
  • T. A. Clarke
    • 1
  • M. Moloney
    • 1
  1. 1.Department of PaediatricsRotunda HospitalDublin 1

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