Summary
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1.
Narphen is a potent analgesic for use during anaesthesia, and absence of restlessness in the post-operative period would suggest a prolongation of effect.
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2.
A pethidine-like respiratory depression occurs, which can be reversed by lethidrone, without any noticeable reduction in analgesia.
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3.
The patient can be maintained in adequate acid-base balance for long periods of anaesthesia with spontaneous respiration.
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4.
The drug is remarkably free from unpleasant side effects. It causes no cardiovascular depression, and minimal post-operative sequelae.
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5.
The recovery time is rapid.
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References
May, E. L. and Eddy, N. B. (1958). A New Potent Synthetic Analgesic.J. Organic Chemistry, 24: 294 (Feb.).
Prevoznik, S. J. and Eckenhoff, J. E. (1960). The Use of Phenazocine in Surgical Patients.Surg. Gynaec. Obstet., 110: 669.
Jolly, C. (1962). Phenazocine with Nitrous Oxide Anaesthesia.B.J. A., 34: 57.
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Based on a joint-paper (with Dr. B. P. de Brit) read at the Royal Academy of Medicine in Ireland on 15th November, 1962.
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Macpherson, M. Some observations on the use of phenazocine (narphen) in Anaesthesia. Ir. J. Med. Sc. 38, 289–293 (1963). https://doi.org/10.1007/BF02953067
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DOI: https://doi.org/10.1007/BF02953067