Summary
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(1)
A capillary permeability test is described which is a modified Goethlin method, and differs from those used by other workers in many respects.
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(2)
It was shown by this test that the pregnant women and the women who had aborted showed a tendency to suffer from abnormal capillary permeability three to four times greater than the ordinary normal adult. The women after parturition showed only a small rise of abnormality in this respect.
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(3)
The test cannot be used for patients who suffer from a high diastolic blood pressure; for this reason the toxæmic conditions of pregnancy could not be investigated to any extent.
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(4)
90 per cent. of pregnant women suffering from iron deficiency anæmia exhibited well-marked abnormal capillary permeability.
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(5)
There is no evident relationship between capillary permeability and gingivitis.
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(6)
The possibilities of attributing capillary deficiency to avitaminosis C have been discussed.
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The suggestion is made that the test should be of great value in determining rapidly the adequacy or inadequacy of a person’s nutritional state. This seems to be a reasonable thing to do if one keeps in mind the many arguments which point to the possibility that more than one food factor is responsible for the maintenance of capillary health.
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Additional information
From the Department of Physiology and Biochemistry, Trinity College, Dublin, and the Rotunda Hospital, Dublin.
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Kawerau, E. The capillary permeability test in pregnancy. Ir J Med Sci 17, 58–70 (1942). https://doi.org/10.1007/BF02952806
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DOI: https://doi.org/10.1007/BF02952806