Current Oncology Reports

, Volume 9, Issue 1, pp 55–59 | Cite as

Statistical issues in clinical trial design

  • Kenneth R. Hess


This paper reviews some of the more salient recent developments in statistical aspects of clinical trial design methodology and suggests that more emphasis be placed on rigorous assessments of the new methodologies to place them in the context of existing methods, demonstrate their claimed advantages, and fully disclose their remaining limitations.


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Copyright information

© Current Science Inc. 2007

Authors and Affiliations

  1. 1.Department of Biostatistics and Applied MathematicsThe University of Texas M.D. Anderson Cancer CenterHoustonUSA

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