This paper reviews some of the more salient recent developments in statistical aspects of clinical trial design methodology and suggests that more emphasis be placed on rigorous assessments of the new methodologies to place them in the context of existing methods, demonstrate their claimed advantages, and fully disclose their remaining limitations.
Unable to display preview. Download preview PDF.
References and Recommended Reading
- 16.Cook J:Collection of software to design, assess, and conduct Bayesian clinical trials. http://biostatistics.mdanderson.org/SoftwareDownload. Accessed 7/3006.Google Scholar